ID Q0W189_METAR Unreviewed; 262 AA.
AC Q0W189;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=fructose-bisphosphate aldolase {ECO:0000256|ARBA:ARBA00013068};
DE EC=4.1.2.13 {ECO:0000256|ARBA:ARBA00013068};
GN Name=fbaB-2 {ECO:0000313|EMBL:CAJ37854.1};
GN ORFNames=RRC80 {ECO:0000313|EMBL:CAJ37854.1};
OS Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanocellales; Methanocellaceae; Methanocella.
OX NCBI_TaxID=351160 {ECO:0000313|EMBL:CAJ37854.1, ECO:0000313|Proteomes:UP000000663};
RN [1] {ECO:0000313|EMBL:CAJ37854.1, ECO:0000313|Proteomes:UP000000663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22066 / NBRC 105507 / MRE50
RC {ECO:0000313|Proteomes:UP000000663};
RX PubMed=16857943; DOI=10.1126/science.1127062;
RA Erkel C., Kube M., Reinhardt R., Liesack W.;
RT "Genome of rice cluster I archaea -- the key methane producers in the rice
RT rhizosphere.";
RL Science 313:370-372(2006).
CC -!- SIMILARITY: Belongs to the DeoC/FbaB aldolase family.
CC {ECO:0000256|ARBA:ARBA00008116}.
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DR EMBL; AM114193; CAJ37854.1; -; Genomic_DNA.
DR RefSeq; WP_012034736.1; NC_009464.1.
DR AlphaFoldDB; Q0W189; -.
DR STRING; 351160.RRC80; -.
DR GeneID; 5145309; -.
DR KEGG; rci:RRC80; -.
DR PATRIC; fig|351160.9.peg.427; -.
DR eggNOG; arCOG04044; Archaea.
DR OrthoDB; 50091at2157; -.
DR Proteomes; UP000000663; Chromosome.
DR GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:UniProtKB-EC.
DR GO; GO:0016836; F:hydro-lyase activity; IEA:InterPro.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:InterPro.
DR CDD; cd00958; DhnA; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR010210; ADH_synthase.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR InterPro; IPR041720; FbaB-like.
DR NCBIfam; TIGR01949; ADH_synth; 1.
DR PANTHER; PTHR47916:SF1; 3-HYDROXY-5-PHOSPHONOOXYPENTANE-2,4-DIONE THIOLASE-RELATED; 1.
DR PANTHER; PTHR47916; FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1; 1.
DR Pfam; PF01791; DeoC; 1.
DR PIRSF; PIRSF038992; Aldolase_Ia; 1.
DR SMART; SM01133; DeoC; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:CAJ37854.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000663}.
FT ACT_SITE 146
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
FT ACT_SITE 177
FT /note="Schiff-base intermediate with dihydroxyacetone-P"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
SQ SEQUENCE 262 AA; 27758 MW; D5CA9EB5260B0DDD CRC64;
MNTGKCIRLG RIINRQSKKT VMVPVDHGVT LGPVTGLSDI RQSMIAAGEG GANAMIMHKG
IAKECYAGHQ KNTGLIIHLS ASTTLSTDPD YKILVASPLE ALKLGADAVS IHVNVGSDKE
FAMLDDLGRI SRESEELGLP LLAMMYARGK NIHNQYDADL IAHACRVGAE LGADLIKTNY
SGDPDSFKKV VKGCPVPVLV AGGLRTGSDL ELLEKIRGAM EAGAGGVAIG RNVFMHENPV
LMVRRISAVV HNGLSPAEAM KL
//
