ID Q0W6I2_METAR Unreviewed; 623 AA.
AC Q0W6I2;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=RCIX604 {ECO:0000313|EMBL:CAJ36011.1};
OS Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanocellales; Methanocellaceae; Methanocella.
OX NCBI_TaxID=351160 {ECO:0000313|EMBL:CAJ36011.1, ECO:0000313|Proteomes:UP000000663};
RN [1] {ECO:0000313|EMBL:CAJ36011.1, ECO:0000313|Proteomes:UP000000663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22066 / NBRC 105507 / MRE50
RC {ECO:0000313|Proteomes:UP000000663};
RX PubMed=16857943; DOI=10.1126/science.1127062;
RA Erkel C., Kube M., Reinhardt R., Liesack W.;
RT "Genome of rice cluster I archaea -- the key methane producers in the rice
RT rhizosphere.";
RL Science 313:370-372(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; AM114193; CAJ36011.1; -; Genomic_DNA.
DR AlphaFoldDB; Q0W6I2; -.
DR STRING; 351160.RCIX604; -.
DR KEGG; rci:RCIX604; -.
DR eggNOG; arCOG06219; Archaea.
DR eggNOG; arCOG06515; Archaea.
DR Proteomes; UP000000663; Chromosome.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF13426; PAS_9; 3.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CAJ36011.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000663};
KW Transferase {ECO:0000313|EMBL:CAJ36011.1}.
FT DOMAIN 86..138
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 138..208
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 212..262
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 263..323
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 397..617
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 623 AA; 70077 MW; D038BCF081998EAA CRC64;
MLVCRMRDLS ELGSFAAEAI KNDTVSFIAW QRDGSIITVN PPFYELTGQS QEQVEKELWP
GKFTTQESKA HILAGMDDQD LGREARKQEV SIVRADGTLL PVELIINRYQ PAGGPVPIYY
AFITEIVERK RSIRELAEKE ELFRALSETA LAAVLLVQNN RVIYANPEAM EMVGYSSDDL
KNIYYWDLIH PDFKDEIIKY GDLLLHGKSL PARFEIKFVR KDGEERWCDV SVGPVVYKGK
MSGVITALDI TERKKSDLAL KESEEKFRVL SELSPMAIFM YQGTKLIYAN LTATMFTGYS
REEIVQKDFW EMVHPKYKDM VRQYGLARQR GEPVPAEYEI EYITKDGELR WAQFTAGQIE
YLGKPAGIVT AIDTTERKHY EIALADAKAQ AELYVDLMGH DINNMNQASL GFLEMATDKL
LATGYLSEED LQLITNAVDS LKSSSSLIDS VRKLQKEKRG GLAPVVIDVT RILGDVKSQF
SAVPGRNINI NYSAQSHCKV RANELVRDVF VNLVGNAIKH SSGDLTINIF VKSVAEQGQL
FCRIDIDDTG PGISDERKQA IFQRSVRDQS KLTGKGLGLY LVRTLVDDYK GRIWVEDRVP
GDYSKGARFV VLLPAVADSA TNN
//
