ID Q0WEJ9_YERPE Unreviewed; 1280 AA.
AC Q0WEJ9;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=ATP-dependent helicase {ECO:0000313|EMBL:CAL20950.1};
GN Name=hrpA {ECO:0000313|EMBL:CAL20950.1};
GN OrderedLocusNames=YPO2322 {ECO:0000313|EMBL:CAL20950.1};
OS Yersinia pestis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632 {ECO:0000313|EMBL:CAL20950.1, ECO:0000313|Proteomes:UP000000815};
RN [1] {ECO:0000313|EMBL:CAL20950.1, ECO:0000313|Proteomes:UP000000815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis {ECO:0000313|Proteomes:UP000000815};
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Leather S., Karlyshev A.V., Moule S.,
RA Oyston P.C.F., Quail M., Rutherford K., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
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DR EMBL; AL590842; CAL20950.1; -; Genomic_DNA.
DR PIR; AC0283; AC0283.
DR RefSeq; YP_002347289.1; NC_003143.1.
DR AlphaFoldDB; Q0WEJ9; -.
DR STRING; 214092.YPO2322; -.
DR PaxDb; 214092-YPO2322; -.
DR KEGG; ype:YPO2322; -.
DR PATRIC; fig|214092.21.peg.2727; -.
DR eggNOG; COG1643; Bacteria.
DR HOGENOM; CLU_001832_3_3_6; -.
DR OMA; YERVTLY; -.
DR Proteomes; UP000000815; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd17989; DEXHc_HrpA; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:CAL20950.1};
KW Hydrolase {ECO:0000313|EMBL:CAL20950.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000815}.
FT DOMAIN 68..231
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 255..425
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1280 AA; 146494 MW; 31AC5FF4944A6D38 CRC64;
MLRDQQRIQR RLHSARKINN PDAIQAITHE IEAEIAIAMQ RVTRRRAACP AISYPDNLPV
SQKKQDIYNA IRDHQVIIVA GETGSGKTTQ LPKICLELGR GVKGVIGHTQ PRRLAARTVA
NRIADELDTS LGGCVGYKVR FNDQVGENTL VKLMTDGILL AEIQQDRLLM QYDTLIIDEA
HERSLNIDFI LGYLRELLPK RPDLKVIITS ATIDPQRFSQ HFNNAPIIEV SGRTYPVEVR
YRPIVDDADD VDRDQLQAIF DAVDELGRES AGDILIFMSG EREIRDTADA LIKQNLPHTE
VLPLYARLSN SEQNRVFQSH HGRRIVLATN VAETSLTVPG IKYVIDPGTA RISRYSFRTK
VQRLPIEPIS QASANQRKGR CGRVSDGICI RLYSEQDFLS RPEFTDPEIL RTNLASVILQ
MTSLGLGDIA AFPFVEAPDK RNIQDGVRLL EELGAIQTAS NGHQQLTPLG RQLAQLPVDP
RLARMVLQAQ KSGCVRELMI ITSALSIQDP RERPVDKQQA SDEKHRRFAD KDSDFLAFVN
LWDYLKEQQK ALSSAQFRKL CRSDYLNYLR VREWQDIYTQ LRQVVKELGI PVNSVAADYR
SVHTAILTGL LSHIGQKDVE KQEFTGARNA RFAIFPGSGL FKKPPKWVMV AELVETSRLW
GRIAARIEPE WIEPLAQHLV KHHYSDPHWE KAQGAVMASE KVTLFGLPIV TERKINYGPI
DPLLCRELFI RHGLVEGDWQ TRHAFFRMNL KLLAEVEELE HKSRRRDILV DDETLFNFYD
QRIGRDVISA LHFDSWWKQA SQTKPELLNF EKTMLIKEGA NKVNPLDYPN FWYQGELKLR
LFYQFEPGTD ADGVTVHIPL PILNQIHEQG FDWQIPGIRR ELVIALIKSL PKPVRRNFVP
APNYADAFLA RVTPLETGLL EALERELRRM TGVTVSRDSW QLDQVPDHLK ITFRVLDDKN
RILREGKDLA ALKLQLQEKV QETLSAVADD GIEQNNLHIW SFGDLPICYE QRRGGYEVKA
YPALVDEKDS VAIRLFDTES QQQQAMWQGT RRLLLLNIPS PIKYLHEKLP NKSKLGLYFN
TYGNVMDLID DCIACGVDKL VAQHGGPVWQ EADFARLQEK VRAELNDTVV DIAKQVEQIL
TLVFSINKRL KGRIDISLVL ALSDIKAQLA GLIYRGFVTS NGWKRLPDTL RYLKAIERRL
EKLAVDPHRD RAQMLRIEHV QQVWQQWLNK LPPKRQQDEE VKEVRWMIEE LRVSLFAQQL
GTPYPVSDKR ILQTIEQLSV
//
