ID KNOS8_ORYSJ Reviewed; 341 AA.
AC Q10ED2; Q6AU58; Q9XIV5;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 24-JAN-2024, entry version 104.
DE RecName: Full=Homeobox protein knotted-1-like 8;
DE AltName: Full=Homeobox protein OSH43;
GN Name=OSH43; OrderedLocusNames=Os03g0771500, LOC_Os03g56110;
GN ORFNames=OSJNBa0072F13.3;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Nipponbare; TISSUE=Embryo;
RX PubMed=10488233; DOI=10.1105/tpc.11.9.1651;
RA Sentoku N., Sato Y., Kurata N., Ito Y., Kitano H., Matsuoka M.;
RT "Regional expression of the rice KN1-type homeobox gene family during
RT embryo, shoot, and flower development.";
RL Plant Cell 11:1651-1664(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18430022; DOI=10.1111/j.1742-4658.2008.06424.x;
RA Jain M., Tyagi A.K., Khurana J.P.;
RT "Genome-wide identification, classification, evolutionary expansion and
RT expression analyses of homeobox genes in rice.";
RL FEBS J. 275:2845-2861(2008).
CC -!- FUNCTION: Probable transcription factor that may be involved in shoot
CC formation during embryogenesis. {ECO:0000269|PubMed:10488233}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108,
CC ECO:0000255|PROSITE-ProRule:PRU00559}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q10ED2-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q10ED2-2; Sequence=VSP_036183;
CC -!- DEVELOPMENTAL STAGE: Expressed in globular stage embryo 3 days after
CC pollination (DAP) in a small region just below the center of the
CC ventral portion of the embryo. At coleoptile stages, mainly expressed
CC in the basal and central parts of the ventral side of the embryo, in
CC cells just below the coleoptile, and corresponding to the epiblast and
CC part of the shoot region. At the shoot apex differentiation stage,
CC expressed in the shoot apical meristem (SAM) and the epiblast, but not
CC in the region between the SAM and epiblast. Expressed also in the cells
CC surrounding the ventral side of the root apical meristem. Expression
CC pattern is maintained in subsequent stages after the second leaf
CC primordium is formed. During inflorescence development, expressed only
CC in the corpus of the rachis primordium, but not in the tunica layer
CC (L1). After floral induction, expressed in both tunica and corpus, but
CC not in floral organ primordia. Later in flower development, expression
CC in the corpus of the floral meristem disappears.
CC {ECO:0000269|PubMed:10488233}.
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice
CC site. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TALE/KNOX homeobox family.
CC {ECO:0000255|PROSITE-ProRule:PRU00559}.
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DR EMBL; AB028884; BAA79225.1; -; mRNA.
DR EMBL; AC133450; AAT85041.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF99092.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF99093.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF13321.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS86597.1; -; Genomic_DNA.
DR EMBL; AK107296; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q10ED2; -.
DR SMR; Q10ED2; -.
DR STRING; 39947.Q10ED2; -.
DR PaxDb; 39947-Q10ED2; -.
DR EnsemblPlants; Os03t0771500-01; Os03t0771500-01; Os03g0771500. [Q10ED2-2]
DR Gramene; Os03t0771500-01; Os03t0771500-01; Os03g0771500. [Q10ED2-2]
DR eggNOG; KOG0773; Eukaryota.
DR InParanoid; Q10ED2; -.
DR OMA; TEFFESV; -.
DR OrthoDB; 3180467at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR Genevisible; Q10ED2; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR005539; ELK_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR005540; KNOX1.
DR InterPro; IPR005541; KNOX2.
DR PANTHER; PTHR11850:SF87; HOMEOBOX PROTEIN KNOTTED-1-LIKE 7; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF03789; ELK; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF03790; KNOX1; 1.
DR Pfam; PF03791; KNOX2; 1.
DR SMART; SM01188; ELK; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM01255; KNOX1; 1.
DR SMART; SM01256; KNOX2; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51213; ELK; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Homeobox; Nucleus; Reference proteome.
FT CHAIN 1..341
FT /note="Homeobox protein knotted-1-like 8"
FT /id="PRO_0000360010"
FT DOMAIN 207..227
FT /note="ELK"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00559"
FT DNA_BIND 228..291
FT /note="Homeobox; TALE-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..147
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 188..192
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_036183"
SQ SEQUENCE 341 AA; 37236 MW; B15D3179F0840FEB CRC64;
MESFASLAGG GSSSTTARLP ELISPENPDH ISPPPLLYQL LAGPESSARQ HGHDGHHHGG
GGGEAAAAAV QGQVSPAGAE AAVKAEIMSH PQYSALLAAY LGCKKVGAPP DVLTKLTAVP
AAQQLDEADG HPRRRHEPQR DDDPDQLDQF MDAYCSMLTR YREELERPIL EAAEFFSRVE
TQLDSLAESN CEGTGSSEEE QDPSDKQLKH QLLRKYGGSL GDLRQVFSKR TKKGKLPKEA
RQKLLHWWEL HYKWPYPSEM EKMTLAQTTG LDQKQINNWF INQRKRHWKP TPVAGTAFPT
MEAAGGGFRH SGHGGGLAAA AALPLYMGRP FVVDGMYRLG S
//
