ID Q12WC2_METBU Unreviewed; 379 AA.
AC Q12WC2;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN OrderedLocusNames=Mbur_1336 {ECO:0000313|EMBL:ABE52254.1};
OS Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 /
OS ACE-M).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanococcoides.
OX NCBI_TaxID=259564 {ECO:0000313|EMBL:ABE52254.1, ECO:0000313|Proteomes:UP000001979};
RN [1] {ECO:0000313|Proteomes:UP000001979}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6242 / NBRC 107633 / OCM 468 / ACE-M
RC {ECO:0000313|Proteomes:UP000001979};
RX PubMed=19404327; DOI=10.1038/ismej.2009.45;
RA Allen M.A., Lauro F.M., Williams T.J., Burg D., Siddiqui K.S.,
RA De Francisci D., Chong K.W., Pilak O., Chew H.H., De Maere M.Z., Ting L.,
RA Katrib M., Ng C., Sowers K.R., Galperin M.Y., Anderson I.J., Ivanova N.,
RA Dalin E., Martinez M., Lapidus A., Hauser L., Land M., Thomas T.,
RA Cavicchioli R.;
RT "The genome sequence of the psychrophilic archaeon, Methanococcoides
RT burtonii: the role of genome evolution in cold adaptation.";
RL ISME J. 3:1012-1035(2009).
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DR EMBL; CP000300; ABE52254.1; -; Genomic_DNA.
DR RefSeq; WP_011499399.1; NC_007955.1.
DR AlphaFoldDB; Q12WC2; -.
DR STRING; 259564.Mbur_1336; -.
DR GeneID; 3997552; -.
DR KEGG; mbu:Mbur_1336; -.
DR HOGENOM; CLU_033784_0_0_2; -.
DR Proteomes; UP000001979; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 1.10.150.320; Photosystem II 12 kDa extrinsic protein; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR023874; DNA_rSAM_put.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR010994; RuvA_2-like.
DR PANTHER; PTHR21180; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR21180:SF9; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF12836; HHH_3; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01102; Uncharacterised_Radical_SAM_Su; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 37..278
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 379 AA; 42985 MW; C0D5B110F25685DD CRC64;
MSAYRQNEHH LTLSERMQIL SAGTKYDSCN QSAVCHAFGP DGRCIQLYKT LLSNSCAGEC
AYCPNRCERE TKRAFLEPVE IAKITWSFYR RNAIDGLFLS SGIMGDAEYT SQKQLEVVEL
LRGQGFKGYI NIRVMPGTPK YLLEQIADHA DKFGVNAETT NSVNYSEICP NFDYKNDVLQ
RLKWTRDLIE KKRSEYSGMG KMVGANDTQF VLGAVAESDK EVVKTVHRFM DKYALRRPYF
MSFDPVPDTP LENGSPSPKW REQRLYQMSF LLKDYGLRSS DFDEIYDEYG YLSNADPKEV
LARSQPDRFP VDINSAEMSE LLMVPGIGPI SANRIVRARP IVSEQELCRV GVVVSRARPY
ISINGSRQMN LSSFMGACS
//
