ID Q12ZA1_METBU Unreviewed; 159 AA.
AC Q12ZA1;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Guanine deaminase {ECO:0000313|EMBL:ABE51225.1};
DE EC=3.5.4.3 {ECO:0000313|EMBL:ABE51225.1};
GN OrderedLocusNames=Mbur_0215 {ECO:0000313|EMBL:ABE51225.1};
OS Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 /
OS ACE-M).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanococcoides.
OX NCBI_TaxID=259564 {ECO:0000313|EMBL:ABE51225.1, ECO:0000313|Proteomes:UP000001979};
RN [1] {ECO:0000313|Proteomes:UP000001979}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6242 / NBRC 107633 / OCM 468 / ACE-M
RC {ECO:0000313|Proteomes:UP000001979};
RX PubMed=19404327; DOI=10.1038/ismej.2009.45;
RA Allen M.A., Lauro F.M., Williams T.J., Burg D., Siddiqui K.S.,
RA De Francisci D., Chong K.W., Pilak O., Chew H.H., De Maere M.Z., Ting L.,
RA Katrib M., Ng C., Sowers K.R., Galperin M.Y., Anderson I.J., Ivanova N.,
RA Dalin E., Martinez M., Lapidus A., Hauser L., Land M., Thomas T.,
RA Cavicchioli R.;
RT "The genome sequence of the psychrophilic archaeon, Methanococcoides
RT burtonii: the role of genome evolution in cold adaptation.";
RL ISME J. 3:1012-1035(2009).
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DR EMBL; CP000300; ABE51225.1; -; Genomic_DNA.
DR AlphaFoldDB; Q12ZA1; -.
DR STRING; 259564.Mbur_0215; -.
DR KEGG; mbu:Mbur_0215; -.
DR HOGENOM; CLU_025810_5_2_2; -.
DR Proteomes; UP000001979; Chromosome.
DR GO; GO:0008892; F:guanine deaminase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd01285; nucleoside_deaminase; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR InterPro; IPR016192; APOBEC/CMP_deaminase_Zn-bd.
DR InterPro; IPR002125; CMP_dCMP_dom.
DR InterPro; IPR016193; Cytidine_deaminase-like.
DR PANTHER; PTHR11079:SF161; CMP_DCMP-TYPE DEAMINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11079; CYTOSINE DEAMINASE FAMILY MEMBER; 1.
DR Pfam; PF00383; dCMP_cyt_deam_1; 1.
DR SUPFAM; SSF53927; Cytidine deaminase-like; 1.
DR PROSITE; PS00903; CYT_DCMP_DEAMINASES_1; 1.
DR PROSITE; PS51747; CYT_DCMP_DEAMINASES_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ABE51225.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 4..131
FT /note="CMP/dCMP-type deaminase"
FT /evidence="ECO:0000259|PROSITE:PS51747"
SQ SEQUENCE 159 AA; 17628 MW; 2021C5067ED29FDA CRC64;
MSEHLMEYFM DAAVKEAQKG MRNNEGGPFG AVIVKDDTII SKGHNEVLGT NDPSAHAEIV
AIRKASAALE DFDLSGCELY ATTMPCPMCL SAIMWARIGK IYYGTSTEDV ASLGFDDGDI
YAMLREGVDT SVLSEVKIEC ENCYELFDEW SKKPDKRMY
//
