ID Q13FY3_PARXL Unreviewed; 394 AA.
AC Q13FY3;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=RND efflux pump, membrane fusion protein, CzcB subfamily {ECO:0000313|EMBL:ABE37006.1};
GN ORFNames=Bxe_C1141 {ECO:0000313|EMBL:ABE37006.1};
OS Paraburkholderia xenovorans (strain LB400).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE37006.1, ECO:0000313|Proteomes:UP000001817};
RN [1] {ECO:0000313|EMBL:ABE37006.1, ECO:0000313|Proteomes:UP000001817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LB400 {ECO:0000313|EMBL:ABE37006.1,
RC ECO:0000313|Proteomes:UP000001817};
RX PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V.,
RA Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J.,
RA Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T.,
RA Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
RT "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome
RT shaped for versatility.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP000272; ABE37006.1; -; Genomic_DNA.
DR RefSeq; WP_011494253.1; NZ_CP008761.1.
DR AlphaFoldDB; Q13FY3; -.
DR STRING; 266265.Bxe_C1141; -.
DR KEGG; bxb:DR64_8659; -.
DR KEGG; bxe:Bxe_C1141; -.
DR PATRIC; fig|266265.5.peg.8895; -.
DR eggNOG; COG0845; Bacteria.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000001817; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR PANTHER; PTHR30469:SF37; RAGD PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..302
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 394 AA; 41025 MW; 92C7B7F41FE5D137 CRC64;
MSSEPIVTSQ PVPRRRLVII GVIGIAIAIT VVAAGVTLRA VDARNLKSWT NAQTVPTVTV
IHPVSAANGP TLDLPSHLEA YSRAPIFARV SGYLKSWDAE IGTPVKAGQL LAVIESPELD
QQLLQARADL ASAQANAALA GTTAKRWQAL LGTDSVAQQE VDERTGDYTA KKAAVAAAQA
NVDRLLATKG FERIVAPFDG VVTARDTDVG ALINAGSGGA GQELFVVSDV KRLRVYVQVP
QSFAPDVRSG TTATLTVPEY PGQRFTARVV ASADSVNAAS GTTLVQLLVD NSDGKLLPGG
FASLQFKLPV QQNAVRVPAS ALVFDAHGLR VATLGANNQV VFRTVTINRD FGDSVEIGSG
LDATDRVIDT PPDGLVDGDR VQLASSATKG GAHG
//
