ID Q13HL1_PARXL Unreviewed; 610 AA.
AC Q13HL1;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit {ECO:0000313|EMBL:ABE36428.1};
DE EC=1.6.5.3 {ECO:0000313|EMBL:ABE36428.1};
GN ORFNames=Bxe_C0528 {ECO:0000313|EMBL:ABE36428.1};
OS Paraburkholderia xenovorans (strain LB400).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE36428.1, ECO:0000313|Proteomes:UP000001817};
RN [1] {ECO:0000313|EMBL:ABE36428.1, ECO:0000313|Proteomes:UP000001817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LB400 {ECO:0000313|EMBL:ABE36428.1,
RC ECO:0000313|Proteomes:UP000001817};
RX PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V.,
RA Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J.,
RA Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T.,
RA Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
RT "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome
RT shaped for versatility.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
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DR EMBL; CP000272; ABE36428.1; -; Genomic_DNA.
DR AlphaFoldDB; Q13HL1; -.
DR STRING; 266265.Bxe_C0528; -.
DR KEGG; bxe:Bxe_C0528; -.
DR eggNOG; COG1894; Bacteria.
DR eggNOG; COG1905; Bacteria.
DR Proteomes; UP000001817; Chromosome 3.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd03083; TRX_Fd_NuoE_hoxF; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 1.10.10.1590; NADH-quinone oxidoreductase subunit E; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR041921; NuoE_N.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01257; 2Fe-2S_thioredx; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00644; COMPLEX1_51K_1; 1.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:ABE36428.1}.
FT DOMAIN 488..533
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|SMART:SM00928"
SQ SEQUENCE 610 AA; 66393 MW; 6BB64A03500C6018 CRC64;
MAVEPDLQLS PGPASLKSGS VDALLLRARH DPHALVQILR EAQARHTWLS RELLGYIAGA
LGLTLAHVEG VATFYRFFHT SPAGEYRVLF SDNITDRMQG NAALLDDLCR RLGVQRGQMR
EDGRVSVDFC SCTGLCDQGP SLLINHHQVV TRLDAGRVAQ LAEFIESRVP AAQWPAHWFR
VDDHVRRADV LLGTPLIPGA AIAAALARGV PALFDEMNRS NLRGRGGAGF VTGMKWRLCR
DAPGTEHYIV CNADEGEPGT FKDRVLLTRH PDMVVEGMTI GALAIGARRG MLYLRGEYRY
LLEPLLDVLQ RRREAHLLGA SILGHAGFDF DIDIHVGAGA YVCGEESALI ESLEGKRGTP
RIRPPFPAEH GYLQQPTVVD NVETLCAATH VALQGGAWWS AIGTPKSTGT SLHSVSGDCE
RPGIYEYPLG TSVDRILEDC GARDTQAVQV GGPSGKCLSA IEFGHRIAFE DVPSAGAFMV
FDRSRDMFEV ARNYAGFFAE ESCGFCTPCR VGTALVVKSM DKLAAGRGSR HDVELLSDID
ILMHGTTHCG LGGSACNALH DTIVKFRPAY ERRLKSLEFE PAFDLDAEIE AARRVTGRDD
DTVTQRESAA
//
