ID Q13WJ3_PARXL Unreviewed; 348 AA.
AC Q13WJ3;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Nitrilase {ECO:0000313|EMBL:ABE31546.1};
DE EC=3.5.5.7 {ECO:0000313|EMBL:ABE31546.1};
GN ORFNames=Bxe_A1408 {ECO:0000313|EMBL:ABE31546.1};
OS Paraburkholderia xenovorans (strain LB400).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE31546.1, ECO:0000313|Proteomes:UP000001817};
RN [1] {ECO:0000313|EMBL:ABE31546.1, ECO:0000313|Proteomes:UP000001817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LB400 {ECO:0000313|EMBL:ABE31546.1,
RC ECO:0000313|Proteomes:UP000001817};
RX PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V.,
RA Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J.,
RA Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T.,
RA Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
RT "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome
RT shaped for versatility.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily.
CC Nitrilase family. {ECO:0000256|ARBA:ARBA00008129}.
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DR EMBL; CP000270; ABE31546.1; -; Genomic_DNA.
DR RefSeq; WP_011489117.1; NZ_CP008760.1.
DR AlphaFoldDB; Q13WJ3; -.
DR STRING; 266265.Bxe_A1408; -.
DR KEGG; bxe:Bxe_A1408; -.
DR PATRIC; fig|266265.5.peg.3162; -.
DR eggNOG; COG0388; Bacteria.
DR OrthoDB; 9803803at2; -.
DR Proteomes; UP000001817; Chromosome 1.
DR GO; GO:0018762; F:aliphatic nitrilase activity; IEA:UniProtKB-EC.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR CDD; cd07564; nitrilases_CHs; 1.
DR Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR InterPro; IPR003010; C-N_Hydrolase.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR InterPro; IPR023919; Nitrilase.
DR InterPro; IPR000132; Nitrilase/CN_hydratase_CS.
DR InterPro; IPR044149; Nitrilases_CHs.
DR NCBIfam; TIGR04048; nitrile_sll0784; 1.
DR PANTHER; PTHR46044; NITRILASE; 1.
DR PANTHER; PTHR46044:SF16; NITRILASE (AFU_ORTHOLOGUE AFUA_6G13450); 1.
DR Pfam; PF00795; CN_hydrolase; 1.
DR SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR PROSITE; PS50263; CN_HYDROLASE; 1.
DR PROSITE; PS00921; NITRIL_CHT_2; 1.
DR PROSITE; PS50007; PIPLC_X_DOMAIN; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ABE31546.1}.
FT DOMAIN 11..277
FT /note="CN hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS50263"
FT REGION 325..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 348 AA; 38119 MW; B77CC93C32A8DBDE CRC64;
MSDKSTGKRI VRAAAVQIAP DFERSGGTLE KVCEAIEQAA REGVQLIVFP ETFVPYYPYF
SFVRPPVASG ADHMKLYEEA VVVPGPVTQA VAEQARLHRM VVVLGVNERD HGSLYNTQLI
FDVDGQIVLK RRKITPTFHE RMIWGQGDAA GLTVARTAVA RVGALACWEH YNPLARYALM
TQHEEIHCSQ FPGSLVGPIF ADQIEVTIRH HALESGCFVV NATGWLSEAQ IASVTPDTNL
QRALRGGCNT AIVSPEGQHL AEPLREGEGM VIADLDMALI TKRKRMMDSV GHYARPELLS
LAINRRPAET VAPMQAWPAV PGADFNSTEG GCDERQRTAV GREPAIDD
//
