ID Q14Q54_SPICI Unreviewed; 340 AA.
AC Q14Q54;
DT 22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT 22-AUG-2006, sequence version 1.
DT 13-SEP-2023, entry version 58.
DE RecName: Full=nicotinate phosphoribosyltransferase {ECO:0000256|ARBA:ARBA00013236};
DE EC=6.3.4.21 {ECO:0000256|ARBA:ARBA00013236};
GN Name=pncB {ECO:0000313|EMBL:CAK98375.1};
GN ORFNames=GL982_08790 {ECO:0000313|EMBL:QIA73640.1}, HHA36_08950
GN {ECO:0000313|EMBL:QJU62379.1}, SCITRI_001750
GN {ECO:0000313|EMBL:APE75616.1}, SPICI01B_128
GN {ECO:0000313|EMBL:CAK98375.1};
OS Spiroplasma citri.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC Spiroplasma.
OX NCBI_TaxID=2133 {ECO:0000313|EMBL:CAK98375.1};
RN [1] {ECO:0000313|EMBL:CAK98375.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GII3-3X {ECO:0000313|EMBL:CAK98375.1};
RA Carle P., Saillard C., Carrere N., Carrere S., Duret S., Eveillard S.,
RA Gaurivaud P., Gourgues G., Gouzy J., Salar P., Verdin E., Breton M.,
RA Blanchard A., Laigret F., Bove J.M., Renaudin J., Foissac X.;
RT "Partial chromosome sequence of Spiroplasma citri reveals extensive viral
RT invasion and important gene decay.";
RL Appl. Environ. Microbiol. 76:3420-3426(2010).
RN [2] {ECO:0000313|EMBL:APE75616.1, ECO:0000313|Proteomes:UP000183717}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R8-A2 {ECO:0000313|EMBL:APE75616.1,
RC ECO:0000313|Proteomes:UP000183717};
RA Davis R.E., Shao J., Gasparich G., Gaynor B., Donofrio N.;
RT "Complete Genome Sequence of Spiroplasma citri R8A2.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QIA73640.1, ECO:0000313|Proteomes:UP000464221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BLH-13 {ECO:0000313|EMBL:QIA73640.1,
RC ECO:0000313|Proteomes:UP000464221};
RA Yokomi R., Chen J., Rattner R., Selvaraj V., Maheshwari Y., Osman F.,
RA Vidalakis G.;
RT "Whole genome sequencing and comparative genomics analyses of six strains
RT of Spiroplasma citri.";
RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:QJU62379.1, ECO:0000313|Proteomes:UP000501133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 {ECO:0000313|EMBL:QJU62379.1,
RC ECO:0000313|Proteomes:UP000501133};
RA Rattner R., Dang T., Mello A.F.S., Espindola A.S., Cardwell K.,
RA Fletcher J., Yokomi R., Vidalakis G.;
RT "Genome-wide analyses of Spiroplamsa citri strains and comparison with
RT other spiroplasmas.";
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O +
CC nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide +
CC phosphate; Xref=Rhea:RHEA:36163, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:32544, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57502, ChEBI:CHEBI:58017,
CC ChEBI:CHEBI:456216; EC=6.3.4.21;
CC Evidence={ECO:0000256|ARBA:ARBA00001240};
CC -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-
CC ribonucleotide from nicotinate: step 1/1.
CC {ECO:0000256|ARBA:ARBA00004952}.
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DR EMBL; CP013197; APE75616.1; -; Genomic_DNA.
DR EMBL; AM285302; CAK98375.1; -; Genomic_DNA.
DR EMBL; CP047428; QIA73640.1; -; Genomic_DNA.
DR EMBL; CP053304; QJU62379.1; -; Genomic_DNA.
DR RefSeq; WP_071937938.1; NZ_CP096807.1.
DR AlphaFoldDB; Q14Q54; -.
DR STRING; 2133.SCITRI_001750; -.
DR GeneID; 54239572; -.
DR KEGG; sck:SCITRI_001750; -.
DR OrthoDB; 9770610at2; -.
DR UniPathway; UPA00253; UER00457.
DR Proteomes; UP000183717; Chromosome.
DR Proteomes; UP000464221; Chromosome.
DR Proteomes; UP000501133; Chromosome.
DR GO; GO:0004516; F:nicotinate phosphoribosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0016763; F:pentosyltransferase activity; IEA:InterPro.
DR GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.90.1170.20; Quinolinate phosphoribosyl transferase, N-terminal domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007229; Nic_PRibTrfase-Fam.
DR InterPro; IPR036068; Nicotinate_pribotase-like_C.
DR InterPro; IPR037128; Quinolinate_PRibosylTase_N_sf.
DR PANTHER; PTHR43202:SF1; NICOTINATE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43202; NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE; 1.
DR PIRSF; PIRSF000484; NAPRT; 2.
DR SUPFAM; SSF51690; Nicotinate/Quinolinate PRTase C-terminal domain-like; 1.
DR SUPFAM; SSF54675; Nicotinate/Quinolinate PRTase N-terminal domain-like; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:CAK98375.1};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:QIA73640.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642};
KW Transferase {ECO:0000313|EMBL:CAK98375.1}.
SQ SEQUENCE 340 AA; 37747 MW; EEE6909C377E4401 CRC64;
MGKIKAGYYS AIYFLKTANI LKNEKPNDLI TMQFFQREEN VILAGVNECV ELLKTEAFNA
ESLEITALTD GDLIQANEPV LKVTGHYYQF GHLEGIIDGI LARQTSIATN CYRVLQAANN
KSVIYMNDRN DYYYNQENDG YAAKIGGITN FVTTAQVTKL VGNYEPIGTV PHALIQAFNG
DLIAALKAYQ KFYPTDKLVA LVDYNNDVIT DTLQVADAFS NLYAVRVDTS QSLIDKYFLG
KEDKYPISEI NGVNKHLIRA LRQALNKAGY RHIKIIVSSG FNAQKIQDFE KEGVPVDIYG
VGESLAKINI GFTGDAVQLN GVDQAKVGRS NITSKRLVKK
//
