ID IHFA_PSEA6 Reviewed; 98 AA.
AC Q15SX9;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE RecName: Full=Integration host factor subunit alpha {ECO:0000255|HAMAP-Rule:MF_00380};
DE Short=IHF-alpha {ECO:0000255|HAMAP-Rule:MF_00380};
GN Name=ihfA {ECO:0000255|HAMAP-Rule:MF_00380};
GN Synonyms=himA {ECO:0000255|HAMAP-Rule:MF_00380};
GN OrderedLocusNames=Patl_2493;
OS Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Paraglaciecola.
OX NCBI_TaxID=3042615;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6c / ATCC BAA-1087;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Karls A.C.,
RA Bartlett D., Higgins B.P., Richardson P.;
RT "Complete sequence of Pseudoalteromonas atlantica T6c.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is one of the two subunits of integration host
CC factor, a specific DNA-binding protein that functions in genetic
CC recombination as well as in transcriptional and translational control.
CC {ECO:0000255|HAMAP-Rule:MF_00380}.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000255|HAMAP-
CC Rule:MF_00380}.
CC -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC {ECO:0000255|HAMAP-Rule:MF_00380}.
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DR EMBL; CP000388; ABG41009.1; -; Genomic_DNA.
DR RefSeq; WP_006991121.1; NC_008228.1.
DR AlphaFoldDB; Q15SX9; -.
DR SMR; Q15SX9; -.
DR STRING; 342610.Patl_2493; -.
DR KEGG; pat:Patl_2493; -.
DR eggNOG; COG0776; Bacteria.
DR HOGENOM; CLU_105066_1_3_6; -.
DR OrthoDB; 9797747at2; -.
DR Proteomes; UP000001981; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR CDD; cd13835; IHF_A; 1.
DR Gene3D; 4.10.520.10; IHF-like DNA-binding proteins; 1.
DR HAMAP; MF_00380; IHF_alpha; 1.
DR InterPro; IPR000119; Hist_DNA-bd.
DR InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR InterPro; IPR005684; IHF_alpha.
DR NCBIfam; TIGR00987; himA; 1.
DR PANTHER; PTHR33175; DNA-BINDING PROTEIN HU; 1.
DR PANTHER; PTHR33175:SF2; INTEGRATION HOST FACTOR SUBUNIT ALPHA; 1.
DR Pfam; PF00216; Bac_DNA_binding; 1.
DR PRINTS; PR01727; DNABINDINGHU.
DR SMART; SM00411; BHL; 1.
DR SUPFAM; SSF47729; IHF-like DNA-binding proteins; 1.
DR PROSITE; PS00045; HISTONE_LIKE; 1.
PE 3: Inferred from homology;
KW DNA recombination; DNA-binding; Transcription; Transcription regulation;
KW Translation regulation.
FT CHAIN 1..98
FT /note="Integration host factor subunit alpha"
FT /id="PRO_0000277754"
FT REGION 52..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 98 AA; 11190 MW; BD8D6A94660729C6 CRC64;
MALTKAEMAE HLFEKLGMNK RDAKDLVEAF FEEVREALES GEQVKLSGFG NFDLRQKSER
PGRNPKTGED IPIKARRVVT FRPGQKLKSR VENTKPTE
//
