ID Q16HP9_AEDAE Unreviewed; 704 AA.
AC Q16HP9;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=AAEL013953-PA {ECO:0000313|EMBL:EAT33778.1};
GN ORFNames=AAEL013953 {ECO:0000313|EMBL:EAT33778.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT33778.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT33778.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT33778.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT33778.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT33778.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT33778.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT33778.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; CH478151; EAT33778.1; -; Genomic_DNA.
DR RefSeq; XP_001664151.1; XM_001664101.1.
DR AlphaFoldDB; Q16HP9; -.
DR STRING; 7159.Q16HP9; -.
DR PaxDb; 7159-AAEL013953-PA; -.
DR VEuPathDB; VectorBase:AAEL023678; -.
DR eggNOG; KOG4441; Eukaryota.
DR HOGENOM; CLU_004253_14_2_1; -.
DR OMA; ATAECYN; -.
DR PhylomeDB; Q16HP9; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF451; KELCH-LIKE PROTEIN 20; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 6.
DR PRINTS; PR00501; KELCHREPEAT.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 2.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 160..227
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 22..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 92..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 704 AA; 77909 MW; 911A8A9AD0109DFC CRC64;
MDMRPTTSLA VCCTTTTTIT TKSKTGAEST SSRSSTATKP TAQEEEVDEG DSSSGQLVST
RGICTLRVKI FLIKHLSKLV ACNKKMFLPV KSNTSPVTTE GTNGEDVTTV TSNSTQTPSD
LSPPNMSGDD ILPQAHHQNP GHCIASFSAI NRMRQNAQLC DVALEVGGET INAHKVILAS
VSPYFYAMFN DDMLERNRDV VTLHDIDPSS LKQLIEYAYS GEITITEENV QVLLPASSLL
QIQSVREACC KFLLRQLHPS NCLGIRSFAD AHSCKELHSR SHRYALQNFQ QVVGTEEFLL
LGFNEVQDLI SNSQLNICSE EKVFVAVLNW VKHDLSERKK HISELMSHVR LPLVNREFLM
SCVETEPLVR EDSHCKELLL EAMKYHLLPE QRSSLVSQRT LERRPEGMRQ YIFAVGGGSL
FAIHNECECY NPKTNAWMTI SPMSSRRSRA GVTALRKLLY VVGGYDGEND LASAECYNPL
TNEWCNITPM GTKRSCLGTC AFDGLLYVCG GYDGASCLAS VERYDPLTAV WTSCPAMNTR
RRYCRVAVLD NCIYALGGFD SSNYQSSVER FDPRVGNWSA VPSMTSRRSS CGVAALDGYL
YCIGGSDGTM CMQTGERFNL RANSWEPISA MHSRRSTHEV VEANGYLYAL GGNDGSSSLN
SVERYEPKVN KWTIVTSMLT RRSSIGASVL ECFNLERGLL QTSI
//
