ID Q16VK8_AEDAE Unreviewed; 808 AA.
AC Q16VK8;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=AAEL009529-PA {ECO:0000313|EMBL:EAT38588.1};
GN ORFNames=AAEL009529 {ECO:0000313|EMBL:EAT38588.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT38588.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT38588.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT38588.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT38588.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT38588.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT38588.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT38588.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH477589; EAT38588.1; -; Genomic_DNA.
DR RefSeq; XP_001660195.1; XM_001660145.1.
DR AlphaFoldDB; Q16VK8; -.
DR STRING; 7159.Q16VK8; -.
DR PaxDb; 7159-AAEL009529-PA; -.
DR VEuPathDB; VectorBase:AAEL004397; -.
DR eggNOG; KOG0510; Eukaryota.
DR HOGENOM; CLU_010276_0_0_1; -.
DR OMA; NVITWIG; -.
DR PhylomeDB; Q16VK8; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:UniProt.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR PANTHER; PTHR47143; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR PANTHER; PTHR47143:SF3; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 359..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 554..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 360..587
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT COILED 733..760
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 808 AA; 93362 MW; 0AECCD61BB74BE36 CRC64;
MMHMQGGANK QLCLGFYQEW VQIKVTVELL EILLRFKEEQ RFERKFLQFK VDEWNVREVI
RLLLHIAVEL DMERSVKTII EHAGQLIFKT VKPITSKKKV LRVCEPDPEH DAKGSELVYR
VELKGLLKKA CERGNVSTLT LLLGHITDRI LVNDDPILVF TLNRAQELWR HEEERAKVLQ
CAEFLAKDQK IHLTRTDNNG NTALHTSLKF GFTDIALDLL QQKYAFLGVR NKDNQTPLDF
ARFEFWKMYF DQCVAIDVRR SYFDRNEIRL NLNGFDPFIF KKRPTKKTSP KDRSEMNLWR
IVEKASSSNV SHQQPQQTYV TEMDPVKIIA KSKELKRLLL HPVIYTFILV KWLRLTKWIY
LNLICTLATV VCFGLHSLDT CNGDNQYSIA LNVITWIGAI YMIGREMVQI LFLRLSYFSS
FENYLDIGTI ISMIIVLLNG CRSILSSLIV IAFALQLTVL IGSLPFNTLS TYMYMFKTVS
ANFMKSFLLF IPLLGAFTFS FFLSYNDRTV PHNSTEDEIP FNTFSSFTDA ALKTLVMTTG
EYEAAGVDFS GGKIILFVLF IFFAPIVILN LINGLAVSDI TAIKEESELI SLRKKVLILE
RYERGLREMP IEFIRRMFPS SFFENHSYII IVKPKELRKI LVQHINPQAE NQRGQKLPKG
EWRVVPNMPG GWLVRGSEGF FVNLKFLKFP LFCTLDEHIM DEALQIADAS IMLREIMDSR
RAEMTSMASM SSFTDTEDKL EEMKAEITKM NRLLMRALQQ KQPTKRKISG NKAKMVREID
EPGDKFTTVT KVAKAVGKFK KGKKKPKS
//
