ID Q16WN3_AEDAE Unreviewed; 415 AA.
AC Q16WN3;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE RecName: Full=TGF-beta family profile domain-containing protein {ECO:0000259|PROSITE:PS51362};
GN Name=5571580 {ECO:0000313|EnsemblMetazoa:AAEL009167-PA};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL009167-PA, ECO:0000313|Proteomes:UP000008820};
RN [1] {ECO:0000313|EnsemblMetazoa:AAEL009167-PA, ECO:0000313|Proteomes:UP000008820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL009167-PA,
RC ECO:0000313|Proteomes:UP000008820};
RG Aedes aegypti Genome Working Group (AGWG);
RA Matthews B.J.;
RT "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AAEL009167-PA}
RP IDENTIFICATION.
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL009167-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR RefSeq; XP_001659788.1; XM_001659738.1.
DR AlphaFoldDB; Q16WN3; -.
DR STRING; 7159.Q16WN3; -.
DR PaxDb; 7159-AAEL009167-PA; -.
DR EnsemblMetazoa; AAEL009167-RA; AAEL009167-PA; AAEL009167.
DR GeneID; 5571580; -.
DR KEGG; aag:5571580; -.
DR VEuPathDB; VectorBase:AAEL009167; -.
DR eggNOG; KOG3900; Eukaryota.
DR HOGENOM; CLU_020515_4_1_1; -.
DR InParanoid; Q16WN3; -.
DR OMA; QPFMVGF; -.
DR OrthoDB; 2912454at2759; -.
DR Proteomes; UP000008820; Chromosome 1.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13761; TGF_beta_BMP5_like; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF298; PROTEIN 60A-RELATED; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 291..415
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 415 AA; 47361 MW; A7D1FE4E7775A234 CRC64;
MNFAIISAFC VLNLIYCVLG GLSGLYVDNG AGQTVMDTMM STDDQLEIEH EILELLGLPE
RPRKRHLHSS ISKSAPQFLL NVYDKLSSDT SNNHNRHVRS ADDVDVLFTE ADNKAIDQSD
IIMTFLNKNH HVSEVRHEKG RRLWFDVNEM EDDAELILAE LRLYQRHELN KYGTDEVNIT
VAVYSIINLD GEKELAKIAE VDLPHYDGWI ELNVTSTVMQ WTTDASSNKG FYIGAYLKNR
PDREIKLDEI GLVNARGDDK YQPFLVAYCR SPQIVKPVLH SLSRSKRNTQ RKRKNKSENR
NPLIELPIDH HKSCQIKTLY VSFKDLNWQD WIIAPEGYGA FFCSGECNFP LNAHMNATNH
AIVQTLVHLM HPSKVPKPCC APTKLIPISV LYHIDESNVN LKKYKNMVVK SCGCH
//
