ID Q17701_CAEEL Unreviewed; 691 AA.
AC Q17701;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 2.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=Nose resistant-to-fluoxetine protein N-terminal domain-containing protein {ECO:0000313|EMBL:CAB01113.2};
GN Name=oac-3 {ECO:0000313|EMBL:CAB01113.2,
GN ECO:0000313|WormBase:C06B3.2};
GN ORFNames=C06B3.2 {ECO:0000313|WormBase:C06B3.2}, CELE_C06B3.2
GN {ECO:0000313|EMBL:CAB01113.2};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB01113.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAB01113.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB01113.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284605; CAB01113.2; -; Genomic_DNA.
DR RefSeq; NP_506446.2; NM_074045.2.
DR AlphaFoldDB; Q17701; -.
DR SMR; Q17701; -.
DR PaxDb; 6239-C06B3-2; -.
DR EnsemblMetazoa; C06B3.2.1; C06B3.2.1; WBGene00007361.
DR GeneID; 182290; -.
DR KEGG; cel:CELE_C06B3.2; -.
DR UCSC; C06B3.2; c. elegans.
DR AGR; WB:WBGene00007361; -.
DR WormBase; C06B3.2; CE42311; WBGene00007361; oac-3.
DR eggNOG; KOG3700; Eukaryota.
DR HOGENOM; CLU_007874_3_2_1; -.
DR InParanoid; Q17701; -.
DR OMA; TSEIEPW; -.
DR OrthoDB; 37922at2759; -.
DR PhylomeDB; Q17701; -.
DR Proteomes; UP000001940; Chromosome V.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR InterPro; IPR002656; Acyl_transf_3_dom.
DR InterPro; IPR006621; Nose-resist-to-fluoxetine_N.
DR PANTHER; PTHR11161:SF67; NRF DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11161; O-ACYLTRANSFERASE; 1.
DR Pfam; PF01757; Acyl_transf_3; 1.
DR Pfam; PF20146; NRF; 1.
DR SMART; SM00703; NRF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..691
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004185746"
FT TRANSMEM 200..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 425..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 529..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 569..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 65..192
FT /note="Nose resistant-to-fluoxetine protein N-terminal"
FT /evidence="ECO:0000259|SMART:SM00703"
SQ SEQUENCE 691 AA; 78643 MW; 7BD493147FF75CC5 CRC64;
MKLPFTFLFC LLKFVCSHSG YLFDYGKIES FEPFSSFINY SHVTPECTKD MKTWISSIEQ
FTAASSDCLF FKNCTASILN ILKDNIYAIQ QYDAFAKIPS AGLLEVSLVF DGSYQECHRI
SGVKYETNYC YVLLVPGRNA NCSGGSIQNA GTSVAFRRAV CMPKSCASSD TVDLYNQLSA
LPLTACATFC SQRDVPKDSA FWGFSAFMFV IVSTVILATT VDYLRESVYD ISSKSIEKSA
SLYRLLYSFS FWTNASTILN VSSQPATHIK CLDCIRGLSM AWVLSGHMLN YFAFADTLMP
IKSFANYFAD YFFMNAVFSV DTFFLVSGIT VAYSFFRLKP TTKTLKSPAT WILFYVHRYV
RLTPPYIIFI GFYAVYALYI QGPLAASLFN FTVLQVEACK ASWWRNLIYI NNFDNGENPC
YGPSWYLAVD TQLYLVAPIL LVALTWTPIA GLVVSMVGCI GSMIIVFILY QKFDMPADSF
NADSSGKFNF YVYQKPWTRC PPYLVGILGG YFLSRFATSP VKLSFVKKLI PMLLAVGLIF
ACLTANIGYD QGDHWSSWTK ATYYNFSRFF WALSVLWIIL SCHYGWAGPI GNFMSHPIWQ
PLGRLSYSAY IVHLMVVYYF LNVGDKPLHF VSTWQVYVYY ILPATILTYI FAFFWSCLFE
IPVVKLEKFL LEILLRKKRL PEKKTGKEIW Q
//
