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Database: UniProt
Entry: Q17828
LinkDB: Q17828
Original site: Q17828 
ID   SUV3_CAEEL              Reviewed;         721 AA.
AC   Q17828; Q2XN00;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 2.
DT   16-OCT-2019, entry version 129.
DE   RecName: Full=ATP-dependent RNA helicase SUV3 homolog, mitochondrial;
DE            EC=3.6.4.13;
DE   Flags: Precursor;
GN   ORFNames=C08F8.2;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for
RT   investigating biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: ATPase and DNA/RNA helicase able to unwind DNA/DNA,
CC       DNA/RNA and RNA/RNA duplexes in the 5'-3' direction.
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}. Nucleus
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the helicase family. {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-3 is the initiator.
CC       {ECO:0000305}.
DR   EMBL; Z73103; CAA97429.1; -; Genomic_DNA.
DR   EMBL; Z73103; CAJ43433.1; -; Genomic_DNA.
DR   PIR; T19103; T19103.
DR   RefSeq; NP_001040911.1; NM_001047446.4.
DR   RefSeq; NP_001040912.1; NM_001047447.2.
DR   SMR; Q17828; -.
DR   IntAct; Q17828; 1.
DR   STRING; 6239.C08F8.2a; -.
DR   EPD; Q17828; -.
DR   PaxDb; Q17828; -.
DR   PeptideAtlas; Q17828; -.
DR   PRIDE; Q17828; -.
DR   EnsemblMetazoa; C08F8.2b.1; C08F8.2b.1; WBGene00007444.
DR   EnsemblMetazoa; C08F8.2b.2; C08F8.2b.2; WBGene00007444.
DR   GeneID; 178022; -.
DR   KEGG; cel:CELE_C08F8.2; -.
DR   UCSC; C08F8.2a; c. elegans.
DR   CTD; 178022; -.
DR   WormBase; C08F8.2a; CE19689; WBGene00007444; -.
DR   WormBase; C08F8.2b; CE05249; WBGene00007444; -.
DR   eggNOG; KOG0953; Eukaryota.
DR   eggNOG; ENOG410XSEY; LUCA.
DR   GeneTree; ENSGT00390000003100; -.
DR   HOGENOM; HOG000175283; -.
DR   InParanoid; Q17828; -.
DR   KO; K17675; -.
DR   OMA; AKTVFPH; -.
DR   OrthoDB; 1106167at2759; -.
DR   PhylomeDB; Q17828; -.
DR   PRO; PR:Q17828; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00007444; Expressed in 5 organ(s), highest expression level in germ line (C elegans).
DR   ExpressionAtlas; Q17828; baseline and differential.
DR   GO; GO:0045025; C:mitochondrial degradosome; IBA:GO_Central.
DR   GO; GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0003678; F:DNA helicase activity; ISS:UniProtKB.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032508; P:DNA duplex unwinding; ISS:UniProtKB.
DR   GO; GO:0000965; P:mitochondrial RNA 3'-end processing; IBA:GO_Central.
DR   GO; GO:0006401; P:RNA catabolic process; IBA:GO_Central.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR022192; SUV3_C.
DR   InterPro; IPR041082; Suv3_C_1.
DR   InterPro; IPR041453; Suv3_N.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF12513; SUV3_C; 1.
DR   Pfam; PF18147; Suv3_C_1; 1.
DR   Pfam; PF18114; Suv3_N; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coiled coil; Complete proteome; Helicase; Hydrolase;
KW   Mitochondrion; Nucleotide-binding; Nucleus; Reference proteome;
KW   Transit peptide.
FT   TRANSIT       1     45       Mitochondrion. {ECO:0000255}.
FT   CHAIN        46    721       ATP-dependent RNA helicase SUV3 homolog,
FT                                mitochondrial.
FT                                /FTId=PRO_0000310551.
FT   DOMAIN      183    321       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      345    501       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND     196    203       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   COILED      691    721       {ECO:0000255}.
SQ   SEQUENCE   721 AA;  81269 MW;  4D86730DA4A44E9F CRC64;
     MQMRRASGVL RVLGGLTQRC STSSTPSSSR FPAMNSRRKR NSVRKTATIE DIVEPRKVKH
     VTQTAAGMGE WIGSLDNTNI HMSLDEFMRR PMVRQLAKEN GINDKLFMRS FKSFREYCTP
     EDLNSVDPGL LILLSDISKG TKDCEMLYPF FLDHAKQVFP HLEAMDDLRI ISDLTRPHNW
     YPEARSVTRK IFFHAGPTNS GKTYHALKRF GEAKSAVFCG PLKLLAAEVF HRTNELGIPC
     DLVTGEERRF AKDNHHPSQH LSSTVEMLST QMRVEVAVID EIQMLRDEQR GWAWTRALLG
     AAADEIHLCG EPAAIDIVKK LLEPIGETVE VRYYERKSPL AIADKAIESY SNIEPGDCIV
     CFSKRSIFFN SKKLEENGIK PAVIYGDLPP GTKLAQAAKF NDPDDECNVL VATDAIGMGL
     NLNIRRVIFN SCTRQTELLP TYAALQIAGR AGRFGTAYAN GVATTMRKED LGTLKAILSE
     KIEPIANVGI APTYDQIETF SFHLPQASFV RLLDLFVSVC SVSDHFFICT VYDMRELAVL
     IDQIPLPLKV RYTFCTSPLN TEDKRTSAVF VKMARRFSTG QALTYEWLID MLEWPPKPAT
     TLNELSLLEQ NYEILDQYMW LSMRFPDMLP DEPRVREASK HLDSMIQEGV ESFMSLLSVG
     ATESKAAGSS KSSEGKRENP SKSEREKPNK RSSILEALLK RADISEDDLE QLREELNKNK
     K
//
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