ID Q17AJ7_AEDAE Unreviewed; 521 AA.
AC Q17AJ7;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=Dynactin subunit 4 {ECO:0000256|ARBA:ARBA00034864};
GN Name=5566227 {ECO:0000313|EnsemblMetazoa:AAEL005254-PA};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL005254-PA, ECO:0000313|Proteomes:UP000008820};
RN [1] {ECO:0000313|EnsemblMetazoa:AAEL005254-PA, ECO:0000313|Proteomes:UP000008820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL005254-PA,
RC ECO:0000313|Proteomes:UP000008820};
RG Aedes aegypti Genome Working Group (AGWG);
RA Matthews B.J.;
RT "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AAEL005254-PA}
RP IDENTIFICATION.
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL005254-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cell cortex
CC {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
CC Cytoplasm, cytoskeleton, stress fiber {ECO:0000256|ARBA:ARBA00004529}.
CC Cytoplasm, myofibril, sarcomere {ECO:0000256|ARBA:ARBA00004204}.
CC -!- SIMILARITY: Belongs to the dynactin subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00034776}.
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DR RefSeq; XP_001650614.1; XM_001650564.1.
DR AlphaFoldDB; Q17AJ7; -.
DR STRING; 7159.Q17AJ7; -.
DR PaxDb; 7159-AAEL005254-PA; -.
DR EnsemblMetazoa; AAEL005254-RA; AAEL005254-PA; AAEL005254.
DR GeneID; 5566227; -.
DR KEGG; aag:5566227; -.
DR VEuPathDB; VectorBase:AAEL005254; -.
DR eggNOG; KOG3896; Eukaryota.
DR InParanoid; Q17AJ7; -.
DR OMA; IYFCRHC; -.
DR OrthoDB; 5483333at2759; -.
DR Proteomes; UP000008820; Chromosome 1.
DR GO; GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005869; C:dynactin complex; IEA:InterPro.
DR GO; GO:0030017; C:sarcomere; IEA:UniProtKB-SubCell.
DR GO; GO:0001725; C:stress fiber; IEA:UniProtKB-SubCell.
DR InterPro; IPR008603; DCTN4.
DR PANTHER; PTHR13034; DYNACTIN P62 SUBUNIT; 1.
DR PANTHER; PTHR13034:SF2; DYNACTIN SUBUNIT 4; 1.
DR Pfam; PF05502; Dynactin_p62; 2.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008820}.
SQ SEQUENCE 521 AA; 58511 MW; 161C0E61700F7FC3 CRC64;
MAFFMLPNVV EYACVCGLLN PLTKLYFCRY CMKLRCGFCV CHEVDSHFCS NCLENIPSSE
AKIRKNRCNT CFNCPSCQHT LSVRAANTII QVPAPEAVKT ESDAGGNGVK KESTPEPSPG
KPIARKLYYL SCLHCRWNTR DVGIPDQPVA TGQWPEPEYA NATRFALLLE HYQSVVLHEK
QEKQELWRRK TPKQSKFPSM TDRTGLTVAM IRRQMGWADS KAQLKSAPLA INKSVASETV
DGLPADIFTK ELTLKKISTL EQRLAHPAKQ PVTVNKLFPQ HKLLSIKRSL RCRQCDHNVI
KSEYNPSSIK YRIAMFATYH VPEVRFVRCE PLIKGQDSFL TLKIINPTIN DMTITIMELP
MEAEEQLMID ELKLAAESSS ASSSLMISGL STSSLTKQAS LMEDPRMVEA KVNGSFRLPD
SSFVINHRDD SAEFDEVVQS QQEDPKFIIW RKANQIAMKL AVQPNEDCNA DNEIVIGFSL
QYTYVNTVVE KSSTPTKGPQ KQALTTRVFV KLGKLSEAAS S
//
