ID Q17DH4_AEDAE Unreviewed; 59 AA.
AC Q17DH4;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=AAEL004223-PA {ECO:0000313|EMBL:EAT44410.1};
GN Name=CECB {ECO:0000313|EMBL:EAT44410.1};
GN ORFNames=AAEL004223 {ECO:0000313|EMBL:EAT44410.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT44410.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT44410.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44410.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT44410.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44410.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT44410.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44410.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU003948}.
CC -!- SIMILARITY: Belongs to the cecropin family.
CC {ECO:0000256|ARBA:ARBA00010680, ECO:0000256|RuleBase:RU003948}.
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DR EMBL; CH477295; EAT44410.1; -; Genomic_DNA.
DR RefSeq; XP_001648690.1; XM_001648640.2.
DR AlphaFoldDB; Q17DH4; -.
DR SMR; Q17DH4; -.
DR STRING; 7159.Q17DH4; -.
DR PaxDb; 7159-AAEL004223-PA; -.
DR VEuPathDB; VectorBase:AAEL029104; -.
DR eggNOG; ENOG502T8YY; Eukaryota.
DR HOGENOM; CLU_187909_1_1_1; -.
DR OMA; IAICNVQ; -.
DR PhylomeDB; Q17DH4; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0019731; P:antibacterial humoral response; IEA:InterPro.
DR GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:UniProt.
DR GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:UniProt.
DR GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR InterPro; IPR000875; Cecropin.
DR InterPro; IPR020400; Cecropin_insect.
DR PANTHER; PTHR38329; CECROPIN-A1-RELATED; 1.
DR PANTHER; PTHR38329:SF1; CECROPIN-A1-RELATED; 1.
DR Pfam; PF00272; Cecropin; 1.
PE 3: Inferred from homology;
KW Antibiotic {ECO:0000256|ARBA:ARBA00023022, ECO:0000256|RuleBase:RU003948};
KW Antimicrobial {ECO:0000256|ARBA:ARBA00022529,
KW ECO:0000256|RuleBase:RU003948};
KW Immunity {ECO:0000256|ARBA:ARBA00022859, ECO:0000256|RuleBase:RU003948};
KW Innate immunity {ECO:0000256|ARBA:ARBA00022588,
KW ECO:0000256|RuleBase:RU003948}; Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..59
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014307815"
SQ SEQUENCE 59 AA; 6316 MW; 6081406573FA91B6 CRC64;
MNFNKLFLIV ILAALLLLGQ TEAGRLKKLG KKIERAGKRV FNAAQKGLPV AAGIKGLGR
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