ID Q17DR6_AEDAE Unreviewed; 2310 AA.
AC Q17DR6;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=AAEL004047-PA {ECO:0000313|EMBL:EAT44598.1};
DE Flags: Fragment;
GN ORFNames=AAEL004047 {ECO:0000313|EMBL:EAT44598.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT44598.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT44598.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44598.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT44598.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44598.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT44598.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44598.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH477291; EAT44598.1; -; Genomic_DNA.
DR RefSeq; XP_001648389.1; XM_001648339.2.
DR STRING; 7159.Q17DR6; -.
DR PaxDb; 7159-AAEL004047-PA; -.
DR VEuPathDB; VectorBase:AAEL026169; -.
DR eggNOG; KOG1428; Eukaryota.
DR HOGENOM; CLU_000562_1_0_1; -.
DR OMA; EYCNSSH; -.
DR PhylomeDB; Q17DR6; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR CDD; cd19799; Bbox2_MYCBP2; 1.
DR CDD; cd16463; RING-H2_PHR; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR004939; APC_su10/DOC_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45943; E3 UBIQUITIN-PROTEIN LIGASE MYCBP2; 1.
DR PANTHER; PTHR45943:SF1; E3 UBIQUITIN-PROTEIN LIGASE MYCBP2; 1.
DR Pfam; PF03256; ANAPC10; 1.
DR SMART; SM01337; APC10; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51284; DOC; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 1308..1487
FT /note="DOC"
FT /evidence="ECO:0000259|PROSITE:PS51284"
FT DOMAIN 2070..2121
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 328..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1720..1747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..456
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAT44598.1"
SQ SEQUENCE 2310 AA; 257432 MW; CF25D3B99C732A4C CRC64;
EQSYEKQFLK DFIYVAAGSP GARLAAWLQP ESRLDPNKCE IKMSQEPLRC GWPSHFIIET
RDQYGDEIFV PGIKVISCLV CRRRRHQNIE VKATLGSNLI SESNRKLHIK SRNDSLYLGG
ATLPPKISYE CTFKEKEKSC LKAITAMKPY QPYSFEELRY CNSIQSKTTE MLTANDLGNN
TYGVFWTPSV PGNYSLTITI DGVCVEEIYR VDVIDAGLPP LSQETTLKKV QPPTKLRKFI
AKNSAGLRVR LHPTLQSDQI GIVKLNGIVS YIDEMENDDG LWVRLSTESI REHCTSSWFP
TEAWCLQYNQ HLGKTLLHPI LESSSTKALM EQVDQSSPTT SDANEENENT IDYFDFMKTD
RPGDEGPGSA NGEESATVKM LPITDASEDS SGSAPNINIA NLNQSNIGAA IAGVVGGGAK
KMQALQKWLK GDSFDENDSP RKRRNDGGDM RANGNRSFDR SRSVSPEIFS CMSKLLKCKS
IFLVNYYVFH VTSEQDRKST ENLSVPETGF ASAIPFNNKS LKIESKELPK RALSPSIAET
LRAVFSAFLW HEGLVHDAMA CASFLKFHPS ISKKESENMP VGNPHENLLT REQKVLQRHS
VEISNAGSYL NIRPSTLETL AKIGNCCVHN RKLRNRNVSH ELVFPIKLAD IFSSKDGEYP
QPSALPPALR CLVYVWDQLC CNFIHLVETN SNDKEMICSE IDKNLNLFSS SSLMSNKSGE
EKSSNAPKVP GQKKVEDGCW CELCDVFLPI PVTYHMRIVH PGCGKYAKGK GYNSIGVYCE
GWAGNCGDGG QGVSSWYLMC EKCRQKYVNS AKVSNNVNYN GASNKTEGGS NVLIGFGAES
TIPSELFTIM KENSFFLLEL NSYNGGSGNL KNNNKSSISG LINKSSNNAS DGAALQEQSS
NRYKTGDLND SYDSRLTFIW VLPYCIMLII LLFAVKKDSY KNLYESSSEL LWPPPEMLSC
LETLGAKSNN DLSYNLLGMN MTDMHAFDFK VCVPNFIVIE DVSMEVTESY IKNLQTSPAI
PSTSKFHRSF SMGQGWNTPQ NKLISDYNQH SKLENGAKNE GTPNVVLRRK KQCTCTSGDS
NLLNYPSVNL QKLVPDHLLN NKSTEKIKNA DDKSDGSGSN GSNSAYKLDL HAGALSLLNR
PSMTFMLEKH DLKKLRYSMT RNLRKTVCNI YSLQALNWLL RSVTQPIGLH DIMWWFISSL
SYSTHDSEDE PKLDEGVLGL EHPGSNQFNG PLSQTLSQSL HCLLQTIADL TLLLPSGSSL
QKTAVQCFGL KFKQSDHQFL HRSHVFGNIS KILSKSEEQN DDNLAPSVAM LNSYSNAADQ
DESIRISLLS DVTIAFDLIV SSRPALAGSL LDNSTETFWE SDEEDRNKPK IVELSMNRPN
YKCKAICIHI DNSRDIGSKV SSIQLFGGSS FGETSLLKTI DVDPLACCWI TVPVTEAECT
HYRLEFRGPE ATLRVRQLKL FGYSVEDKAA QLKQNIKSTS ANYIQQKNCE AETLRVFRLL
TGQVFGKLIL ESGKSFGYNT PTSSKINESA VISSSTESLD LREHMVGILF SRSKLSHLQK
QIIVHIVHAI QKEALRSREE WEHNVMFSAD NETDFEENLK INDTYCFEML SMVLALSGSA
VGRSYLSHQH GLLKDLFSLL HTGSDRVQRQ VTALIRRILP EISPETLCEL LGVEKVPETD
FNLLSQNNET FNMNKCGILD IFLAVIAKAL QVQIKVKNNS NKNPPSMKLS TDPERPTTTL
ATKGSNSPAV EQYDFEVSSS DFLDDKTNDE NSVDFDEAIK SKPGIRVEPV IKPRWFLNGT
ISSKQAENIM ILIRDMAHGK LSDKWSMITK AAIAECILNI TRLSDVYRVP ETCMTTPTLW
LALASLCVLD RDHVEKLSSS QWSKQSESRP LCSNHDDDVT YAMIICSLCG SLCSDCDRFL
HLNRKTRNHY RTVCKEEEEA IRVELHESCG RAKLFWLLAL VDSKTLKGML EFRNGNNTLV
CDPPNAIGVC RFCGVTGNTG LLAVGNVCVD QQCQEYAASA CTKVHHCGHL CGGIINEEKC
LPCLQQKCLT SESKANGKEP KLTQDADDMC MICFTEALSS APSIQLDCGH VFHFHCCKAV
LTRRWNGPRI SFGFSQCPIC KMDIQNSALG DILESIVSLK ADVKRKALMR LEYEGLAKNL
DSKDLAAYAM ERYAYYVCSQ CEKAYYGGEA RCDAELGENY NPQELVCGGC SDVVKAKMCP
KHGTDFLEYK CRYCCSVAVF FCFGTTHFCD TCHDDFQRLT NIPKNKLPKC PAGPKAKQLI
GEECPLHVIH PPTGEEFALG CGICRNAHTF
//
