ID Q17IJ9_AEDAE Unreviewed; 599 AA.
AC Q17IJ9;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 123.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:AAEL002343-PB};
GN Name=5565125 {ECO:0000313|EnsemblMetazoa:AAEL002343-PB};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL002343-PB, ECO:0000313|Proteomes:UP000008820};
RN [1] {ECO:0000313|EnsemblMetazoa:AAEL002343-PB, ECO:0000313|Proteomes:UP000008820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL002343-PB,
RC ECO:0000313|Proteomes:UP000008820};
RG Aedes aegypti Genome Working Group (AGWG);
RA Matthews B.J.;
RT "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AAEL002343-PB}
RP IDENTIFICATION.
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL002343-PB};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR RefSeq; XP_001661358.1; XM_001661308.1.
DR AlphaFoldDB; Q17IJ9; -.
DR STRING; 7159.Q17IJ9; -.
DR PaxDb; 7159-AAEL002343-PA; -.
DR EnsemblMetazoa; AAEL002343-RA; AAEL002343-PA; AAEL002343.
DR EnsemblMetazoa; AAEL002343-RB; AAEL002343-PB; AAEL002343.
DR VEuPathDB; VectorBase:AAEL002343; -.
DR eggNOG; KOG3558; Eukaryota.
DR HOGENOM; CLU_009542_2_0_1; -.
DR InParanoid; Q17IJ9; -.
DR OMA; MTCEDAS; -.
DR OrthoDB; 5396877at2759; -.
DR Proteomes; UP000008820; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR PANTHER; PTHR23043; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA; 1.
DR PANTHER; PTHR23043:SF26; PROTEIN TRACHEALESS; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 72..125
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 162..219
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 333..388
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 534..599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..593
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 599 AA; 67350 MW; 9393F8F0F1C17F8D CRC64;
MFPFSSLQVE YSNFHRSSQI MSNALSMTNS GFPHSWIVSG QDFCPITYSS IQSHNSAVSN
NLATVEPGLI ELRKEKSRDA ARSRRGKENY EFYELAKMLP LPAAITSQLD KASIIRLTIS
YLKLKEFSEN GVPSWNKEPI GFQNYTSPQY FNEMFETHLG THILQSLDGF AVSTGVDGRF
LYISETVSIY LGLSQVEMTG SSIFDYIHKG DHAEVEQQLG VKKNSDYYSG YSDEPPEKTV
LKIVKDSKPL PGETYEGDDR AFCVRMKSTL TKRGCHFKSS GYRVILLLCH LRKKNNSTDE
HSEKQTVIGM VGIGIALPPP SLHEIKLESD MFVFRTSLDL TIIHCENRIS SFLDYTADEL
NGKSVYTLCH GQDAPKLKKS HSELIQKGQV LTPFYRILNK NSGYFWIQTC CTMVCQTKNM
SDQTVICVNY IITRPEKENL ILDISQMPNV NHNDYHIGSK SVAAAAAKRA AAAASMEYEM
EVKDKYGELA GSQSDAYLDG HVDHKELIDK SPHKAMGLGM FDKKESLDFK DKHMDREKGC
SNSKQQRLKA GSPMMNMSVN ENQGIDKKSS NGKKNISNRA SVIRVLNKTS SKKILQENH
//
