ID Q17J79_AEDAE Unreviewed; 884 AA.
AC Q17J79;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=AAEL002114-PA {ECO:0000313|EMBL:EAT46728.1};
GN ORFNames=AAEL002114 {ECO:0000313|EMBL:EAT46728.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT46728.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT46728.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT46728.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT46728.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT46728.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT46728.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT46728.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH477234; EAT46728.1; -; Genomic_DNA.
DR RefSeq; XP_001654717.1; XM_001654667.1.
DR AlphaFoldDB; Q17J79; -.
DR STRING; 7159.Q17J79; -.
DR PaxDb; 7159-AAEL002114-PA; -.
DR VEuPathDB; VectorBase:AAEL019577; -.
DR eggNOG; KOG1787; Eukaryota.
DR HOGENOM; CLU_000218_5_0_1; -.
DR OMA; WSIQANQ; -.
DR PhylomeDB; Q17J79; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR046851; NBCH_WD40.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743:SF112; BEACH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF20426; NBCH_WD40; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 74..171
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 184..476
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 626..667
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 709..750
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 884 AA; 98575 MW; 5CEC94356A85425F CRC64;
MRLKLEPDLN HDPHTAASNM RDNTTSTSQT QRLSAELSST IAPAALGDES VDDDILLLEE
EMRNNVEPQV PETSGKEKIV ISQECELITL MTRVKGRLDL TTNQIVFSEI SAIRDDGQRH
DFKFPISQLR ELHLRKFNLR RSALEMFLID QTSYFLNFTT KTRNKIFTKI LSLQPPNILY
GSGRSPAELL RSSGLTQKWV NREISNFEYL MHLNTIAGRS YNDLSQYPVF PWILADYTSD
ILDLTDPKSF RDLSKPIGVV NPKNEIEVRN KYESFEDPSG MIPKFHYGTH YSNSAGVLHY
LIRVEPFTSL HIELQSGRFD VADRQFHSIP QTWKLLMDNP NDVKELIPEF FYFPEFLKNL
NQFDLGILQQ TKERVDNVVL PPWAKSAEDF IAIHRRALES EYVSQNLHHW IDLIFGCKQK
GAKAVEALNV FYYCSYEGAV DLDKITNPVE REAVEGMINN FGQTPSQLLR EHHPKRLSQD
ELTMKLLKLE LKKPDLTLIL DRVNSVNCEL STDKDPVMYL STPRSPPRSF LQTSPDMLIS
VTKNGILGCH SWMSFDKEKG FLLEIDATTS NLKNRKKLIG PFHPSINLNS NLFAVSVDGK
YLYAGGIWDN SVRMFNMARG KVVASAIHHF DVVTCVALDT CGSYLVTGSK DCTCIIWSIS
NGSTSGASSA SNLQPNTAAL NQNLAGNVVG SANVVHLTNN LTPKPVHTLY GHDGPVSCVA
IMTELDIVAS GSLDGTVNVY TVKEGQFVRT INPIGCTGSI IEISFITLSY QGHIAFSALD
DTSHSVHVFS INGVNLGSKY VSGRVTGLST ATDYLVVSDD AGDLTMSRLY GLKPIFDIPL
HIPTQTIVAT GGNTHLLAPL RDGSLAVIGI MQPIAYKKHA VLNV
//
