ID Q17JE8_AEDAE Unreviewed; 505 AA.
AC Q17JE8;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:AAEL002085-PA};
GN Name=5573388 {ECO:0000313|EnsemblMetazoa:AAEL002085-PA};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL002085-PA, ECO:0000313|Proteomes:UP000008820};
RN [1] {ECO:0000313|EnsemblMetazoa:AAEL002085-PA, ECO:0000313|Proteomes:UP000008820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL002085-PA,
RC ECO:0000313|Proteomes:UP000008820};
RG Aedes aegypti Genome Working Group (AGWG);
RA Matthews B.J.;
RT "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AAEL002085-PA}
RP IDENTIFICATION.
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL002085-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR RefSeq; XP_001654558.1; XM_001654508.1.
DR AlphaFoldDB; Q17JE8; -.
DR STRING; 7159.Q17JE8; -.
DR PaxDb; 7159-AAEL002085-PA; -.
DR EnsemblMetazoa; AAEL002085-RA; AAEL002085-PA; AAEL002085.
DR GeneID; 5573388; -.
DR KEGG; aag:5573388; -.
DR VEuPathDB; VectorBase:AAEL002085; -.
DR eggNOG; KOG0157; Eukaryota.
DR InParanoid; Q17JE8; -.
DR OMA; NVKRMAV; -.
DR OrthoDB; 2434474at2759; -.
DR Proteomes; UP000008820; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd20628; CYP4; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24291:SF187; CYTOCHROME P450 4AE1-RELATED; 1.
DR PANTHER; PTHR24291; CYTOCHROME P450 FAMILY 4; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000008820}.
SQ SEQUENCE 505 AA; 58066 MW; B4BBEB18544B72D3 CRC64;
MLFLAIVVGA LLYLVVNFYV TRKPLERMAV HFSGPKPHYL LGNVLEFLNK DLPGIFETMV
GFHRKYGQDI LTWNVLNLNM ISVTSAENVE KVLMAKQTKK SFLYSFVEPW LGQGLLISSG
EKWFQRRKII TPTFHFKILE QFVTVFNKET DTMVENLKKH VDGGEFDIYD YVTLMALDSI
CETSMGTCVN AQKNPTNRYV QNVKRMSVLV LLRTISVLAG SPLLYDILHP HAWEQRKIIK
QLHEFTISVI ESRRRQLEAD KLEQVDFDMN EESLYSKRKM TFLDLLLNVT VEGKPLTNAD
IREEVDTFMF EGHDTTTSGI SFAIYQLALN PQIQDKLYDE IVSILGKNSS NVELTFQTLQ
DFRYLESVIK ESMRLFPPVP FIGRTSVEDM EMNGTTVKAG QEFLVAIYVI HRNPKVYPDP
ERFDPERFSD TAESKRGPYD YIPFSAGSRN CIGQRYAMLE MKVTLIKLLM NYKILPGESM
GKVRVKSDLV LRPDRGIPVK LVARS
//
