ID Q17L55_AEDAE Unreviewed; 550 AA.
AC Q17L55;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 24-JAN-2024, entry version 95.
DE SubName: Full=AAEL001450-PA {ECO:0000313|EMBL:EAT47440.1};
GN ORFNames=AAEL001450 {ECO:0000313|EMBL:EAT47440.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT47440.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT47440.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT47440.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT47440.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT47440.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT47440.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT47440.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH477218; EAT47440.1; -; Genomic_DNA.
DR RefSeq; XP_001659315.1; XM_001659265.1.
DR AlphaFoldDB; Q17L55; -.
DR STRING; 7159.Q17L55; -.
DR PaxDb; 7159-AAEL018236-PA; -.
DR VEuPathDB; VectorBase:AAEL018236; -.
DR eggNOG; KOG1216; Eukaryota.
DR HOGENOM; CLU_018024_2_0_1; -.
DR OMA; CHECELK; -.
DR PhylomeDB; Q17L55; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR Gene3D; 6.20.200.20; -; 3.
DR InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR InterPro; IPR001007; VWF_dom.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR46698; CROSSVEINLESS 2; 1.
DR PANTHER; PTHR46698:SF4; CROSSVEINLESS 2; 1.
DR Pfam; PF08742; C8; 1.
DR Pfam; PF00093; VWC; 3.
DR Pfam; PF00094; VWD; 1.
DR SMART; SM00832; C8; 1.
DR SMART; SM00214; VWC; 3.
DR SMART; SM00215; VWC_out; 3.
DR SMART; SM00216; VWD; 1.
DR SUPFAM; SSF57603; FnI-like domain; 3.
DR PROSITE; PS01208; VWFC_1; 2.
DR PROSITE; PS50184; VWFC_2; 3.
DR PROSITE; PS51233; VWFD; 1.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 13..72
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 84..143
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 150..210
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 214..389
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT REGION 495..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..519
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 62090 MW; EED40DDC49FFBD06 CRC64;
MVNESSIIST YWHGCQLNGQ RVTNEATLSE DPCVKCTCDG RKLTCTKKSC PVLQCPASKQ
IRIPGECCAR CMERREEFKL GLQKHCVIGK AVHFHGATYK ADQCASCECR NGTTFCEKNT
CPVLECAIED QVQGLNDCCP SCPMPAEFKS TCTHRGQVYE NGETWSLNAC TSCECRSGEV
RCARSQCPPQ KCKPNETLIK PKDECCSKCV ESPGVCTVFG DPHYKTFDGY FYSFQGSCKY
QLTADCKDHT FSIRVTNDAR LTKSSSWTKT VTLKLGNLKV NLGQKMRVKI NGSRVDPPYK
LDGVLDVFKS DDGTEVIVST TLGIKLTWDG NNFIQVEVPV IYKNKLCGLC GNYNSVFRDD
LFSRTGVNMT DNVWKFAQSW AVGGEKACTR PRKKELIAKN SQCRPKKFFT FCKILKTDVF
GECNSQLNPE NYFESCKIDM CECPHKQCYC DSLAAYAHEC QRQGIRLPNW RRDTNCYPNA
TNFFTSHHQH LLMQQPVGPQ KKRHQQPTQR QQKNAIVSSQ PNHRKKHRLQ SSHGPLLDPS
TRRAPPPLYS
//
