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Database: UniProt
Entry: Q17M43_AEDAE
LinkDB: Q17M43_AEDAE
Original site: Q17M43_AEDAE 
ID   Q17M43_AEDAE            Unreviewed;       815 AA.
AC   Q17M43;
DT   25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   25-JUL-2006, sequence version 1.
DT   25-APR-2018, entry version 88.
DE   SubName: Full=AAEL001123-PA {ECO:0000313|EMBL:EAT47802.1};
GN   ORFNames=AAEL001123 {ECO:0000313|EMBL:EAT47802.1};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT47802.1, ECO:0000313|Proteomes:UP000008820};
RN   [1] {ECO:0000313|EMBL:EAT47802.1, ECO:0000313|Proteomes:UP000008820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Liverpool/LVPib12 {ECO:0000313|Proteomes:UP000008820};
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M.,
RA   Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J.,
RA   Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P.,
RA   Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V.,
RA   Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B.,
RA   DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M.,
RA   Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H.,
RA   Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S.,
RA   Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D.,
RA   Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A.,
RA   Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D.,
RA   White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A.,
RA   Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J.,
RA   Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B.,
RA   Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS01006510}.
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DR   EMBL; CH477208; EAT47802.1; -; Genomic_DNA.
DR   RefSeq; XP_001652424.1; XM_001652374.1.
DR   ProteinModelPortal; Q17M43; -.
DR   STRING; 7159.AAEL001123-PA; -.
DR   EnsemblMetazoa; AAEL001123-RA; AAEL001123-PA; AAEL001123.
DR   GeneID; 5568592; -.
DR   KEGG; aag:5568592; -.
DR   eggNOG; KOG3676; Eukaryota.
DR   eggNOG; ENOG4110DG4; LUCA.
DR   HOGENOM; HOG000007724; -.
DR   InParanoid; Q17M43; -.
DR   KO; K04974; -.
DR   OMA; YFGQTVL; -.
DR   OrthoDB; EOG091G02JZ; -.
DR   PhylomeDB; Q17M43; -.
DR   Proteomes; UP000008820; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 3.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR024862; TRPV.
DR   PANTHER; PTHR10582; PTHR10582; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SMART; SM00248; ANK; 5.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|SAAS:SAAS00933366};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008820};
KW   Ion channel {ECO:0000256|SAAS:SAAS00790162};
KW   Ion transport {ECO:0000256|SAAS:SAAS00790154};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transport {ECO:0000256|SAAS:SAAS00788392}.
SQ   SEQUENCE   815 AA;  93479 MW;  B8AFB3FB5091A43A CRC64;
     MGNTESNVTS GVKKQAGVST QALYKFVNLK GGGLLVDMMK RAIQNKQYAE IDHAIKTKVE
     PFLYNKGKGK YIPVAQLVLL RNRERPRSKQ LPEIRALENP EEDFDIDAVC PDVTEGEYQR
     NPSGYREVCW NIKERGAVGE TILHLCLLNA TSLHADLAKR LLRFYPKLIN DIYMCDEYYG
     ESVLHVAIVN EDPAMVKYLL DSGSDVDERC CGTFMCPEDQ KATRYDSIET EIICVLPMTN
     YDGYVYWGEY PLSFAACLGQ EECYRLVLAR GADPDNQDSN GNTVLHMLVI YEKISTFDMA
     YEVGSSLDIR NLQNLTPLTL AAKLGRVEMF FHIMNIEREI YWQLGAITCA AYPLALIDTI
     DIETGNINKD SALNLVVFGD KAEHLDLLEG VLIDLLKTKW NSFVKDKFYR QFFVFFWYFC
     VSLVSFTLRR GPMNLEETAA NRTTTSITLK NLTFSDSTNA TLPTLLAADV NEKIVQFIAN
     ETLFDPAVME ENTFFNSKCA TMAYDTLQDK IRLVSEIIIL IGSFLYLVGA LREFRFLGRK
     MFFENLMISP SRVMFLFSCC IMMIVPFLKV LCLIELEDHV AVTIMLTTAP YFLFFCRGFK
     TVGPFVVMIY RMVMGDLLRF VVIYLVFVMG FSQAYYIVFL SFKGEEEGDE NPMPSPMESI
     VAMFLMSLTN FGDYYGALEK TEHEGCAKVL FVIFMVIVAV LLVNLLIAMM GNTYTMIAET
     KNEWQRQWAR IVLVVERGVP PSERLKNFMS YSQPMSDGRR ALVLRLHMTD EDKEEMKEIL
     EMKRVHERLK KKRQVERELR AEQRRLIMEK YANVP
//
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