ID   Q17P00_AEDAE            Unreviewed;       560 AA.
AC   Q17P00;
DT   25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   25-JUL-2006, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN   Name=5563667 {ECO:0000313|EnsemblMetazoa:AAEL000550-PA};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL000550-PA, ECO:0000313|Proteomes:UP000008820};
RN   [1] {ECO:0000313|EnsemblMetazoa:AAEL000550-PA, ECO:0000313|Proteomes:UP000008820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL000550-PA,
RC   ECO:0000313|Proteomes:UP000008820};
RG   Aedes aegypti Genome Working Group (AGWG);
RA   Matthews B.J.;
RT   "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AAEL000550-PA}
RP   IDENTIFICATION.
RC   STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL000550-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1
CC       subfamily. {ECO:0000256|ARBA:ARBA00008959}.
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DR   RefSeq; XP_001647950.1; XM_001647900.1.
DR   AlphaFoldDB; Q17P00; -.
DR   STRING; 7159.Q17P00; -.
DR   PaxDb; 7159-AAEL000550-PA; -.
DR   EnsemblMetazoa; AAEL000550-RA; AAEL000550-PA; AAEL000550.
DR   GeneID; 5563667; -.
DR   KEGG; aag:5563667; -.
DR   VEuPathDB; VectorBase:AAEL000550; -.
DR   eggNOG; KOG2028; Eukaryota.
DR   HOGENOM; CLU_017985_0_2_1; -.
DR   InParanoid; Q17P00; -.
DR   OMA; RIILSQC; -.
DR   OrthoDB; 206891at2759; -.
DR   Proteomes; UP000008820; Chromosome 3.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd18139; HLD_clamp_RarA; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 1.20.272.10; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   Gene3D; 1.10.3710.10; DNA polymerase III clamp loader subunits, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR032423; AAA_assoc_2.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR021886; MgsA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13779:SF7; ATPASE WRNIP1; 1.
DR   PANTHER; PTHR13779; WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF16193; AAA_assoc_2; 1.
DR   Pfam; PF12002; MgsA_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820}.
FT   DOMAIN          171..291
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
SQ   SEQUENCE   560 AA;  62304 MW;  57165F6B24540E35 CRC64;
     MADEPQPSSS CTRSVCPVCD KLFPMADIEA HVDRCLFLNS NDPTAPESTT NGKQELTAAR
     EAKRSFSIFN KSPSVGGNKR PRRTTTDQNG NGGHMSAEDI ERTVIDLSDE EKEKERDKVK
     PDKNKAKVGD EEGSNIPLAE KMRPDELSDY IGQEQIIGKN TVLRTLFEKN TIPSMILWGP
     PGCGKTTLAH IIAAHCKKHG SMKFVKLSAT MSGVNDVKEA VKLAKNDLAF KRKTIMFMDE
     IHRFNKLQQD IFLPHVESGT ITLIGATTEN PSFSLNSALL SRCRVIVLEK LGVEAVMKIL
     KRALPQYKTV MFENNNRVPD IRGLPFVPRM MISAETIRWL AEICDGDARI ALNSLQLALN
     TVAARQDEEE SALKRISLDE IKEGIKKSHL MYDRKGDQHY ELISALHKSI RASDDNAALY
     WCSRMLVSGE DPRYLVRRMI RMASEDIGLA DTNALTVATS TLAAVQAVGM PEADCIIAHC
     AVYLARAPKS REVYNAFNRC KASIGQNKGP MPSVPLHLRN ATTKLMKSLK YGAGYNLQHK
     DESGLQYMPE GLENENYFSE
//