ID Q19058_CAEEL Unreviewed; 298 AA.
AC Q19058;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1996, sequence version 1.
DT 27-MAR-2024, entry version 157.
DE SubName: Full=MaoC-like domain-containing protein {ECO:0000313|EMBL:CCD65898.1};
GN Name=maoc-1 {ECO:0000313|EMBL:CCD65898.1,
GN ECO:0000313|WormBase:E04F6.3};
GN ORFNames=CELE_E04F6.3 {ECO:0000313|EMBL:CCD65898.1}, E04F6.3
GN {ECO:0000313|WormBase:E04F6.3};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD65898.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD65898.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD65898.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- INTERACTION:
CC Q19058; Q19058: maoc-1; NbExp=2; IntAct=EBI-311840, EBI-311840;
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DR EMBL; BX284602; CCD65898.1; -; Genomic_DNA.
DR PIR; T15906; T15906.
DR RefSeq; NP_495494.1; NM_063093.4.
DR AlphaFoldDB; Q19058; -.
DR SMR; Q19058; -.
DR DIP; DIP-24768N; -.
DR STRING; 6239.E04F6.3.1; -.
DR World-2DPAGE; 0020:Q19058; -.
DR EPD; Q19058; -.
DR PaxDb; 6239-E04F6-3; -.
DR PeptideAtlas; Q19058; -.
DR EnsemblMetazoa; E04F6.3.1; E04F6.3.1; WBGene00017123.
DR GeneID; 174181; -.
DR KEGG; cel:CELE_E04F6.3; -.
DR UCSC; E04F6.3; c. elegans.
DR AGR; WB:WBGene00017123; -.
DR WormBase; E04F6.3; CE01215; WBGene00017123; maoc-1.
DR eggNOG; KOG1206; Eukaryota.
DR GeneTree; ENSGT00940000167033; -.
DR HOGENOM; CLU_040078_1_0_1; -.
DR InParanoid; Q19058; -.
DR OMA; FKHTDQE; -.
DR OrthoDB; 2140828at2759; -.
DR PhylomeDB; Q19058; -.
DR Reactome; R-CEL-193368; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol.
DR Reactome; R-CEL-2046106; alpha-linolenic acid (ALA) metabolism.
DR Reactome; R-CEL-389887; Beta-oxidation of pristanoyl-CoA.
DR Reactome; R-CEL-390247; Beta-oxidation of very long chain fatty acids.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00017123; Expressed in larva and 4 other cell types or tissues.
DR GO; GO:0005778; C:peroxisomal membrane; ISS:WormBase.
DR GO; GO:0005777; C:peroxisome; IBA:GO_Central.
DR GO; GO:0044594; F:17-beta-hydroxysteroid dehydrogenase (NAD+) activity; IBA:GO_Central.
DR GO; GO:0018812; F:3-hydroxyacyl-CoA dehydratase activity; ISS:WormBase.
DR GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IBA:GO_Central.
DR GO; GO:0004300; F:enoyl-CoA hydratase activity; IBA:GO_Central.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.
DR GO; GO:0006635; P:fatty acid beta-oxidation; ISS:WormBase.
DR GO; GO:0045087; P:innate immune response; IMP:WormBase.
DR CDD; cd03448; HDE_HSD; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR039569; MaoC-like_dehydrat_N.
DR InterPro; IPR002539; MaoC-like_dom.
DR PANTHER; PTHR13078:SF56; PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2; 1.
DR PANTHER; PTHR13078; PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED; 1.
DR Pfam; PF13452; MaoC_dehydrat_N; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:Q19058,
KW ECO:0007829|PeptideAtlas:Q19058};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 45..130
FT /note="N-terminal of MaoC-like dehydratase"
FT /evidence="ECO:0000259|Pfam:PF13452"
FT DOMAIN 157..276
FT /note="MaoC-like"
FT /evidence="ECO:0000259|Pfam:PF01575"
SQ SEQUENCE 298 AA; 32721 MW; F0A2B5C97ED3494A CRC64;
MDKKTACAHV AEPCEFSYST RDAIIYALGV GARAKEDLCY VYENHEDFKV LPSYIVAPGF
QAHTLMDWPG VEFDLQRVLH GEQYIEVYQP LSAEGKLKSE ARVVDILDKG SGALILGNVT
TYDENGKKIA MQQFSTFQTG SGNFGGDRTS PHEIKAATVP DRAPDAVIEQ KTTVDQAALY
RLGSGDMNPL HVDPEFAKMS GFKTPILHGL CSLGFATRHV IAAWAGNDSD KFKAIKVRFS
SPVLPGQTLV TETWKNGKRI IFQMKVKETG KIVISNAFID LHEASELPTV PIDLASKL
//
