ID Q1AVJ0_RUBXD Unreviewed; 656 AA.
AC Q1AVJ0;
DT 11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2006, sequence version 1.
DT 24-JAN-2024, entry version 94.
DE SubName: Full=Proton-translocating NADH-quinone oxidoreductase, chain L {ECO:0000313|EMBL:ABG04588.1};
DE EC=1.6.99.5 {ECO:0000313|EMBL:ABG04588.1};
GN OrderedLocusNames=Rxyl_1627 {ECO:0000313|EMBL:ABG04588.1};
OS Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1).
OC Bacteria; Actinomycetota; Rubrobacteria; Rubrobacterales; Rubrobacteraceae;
OC Rubrobacter.
OX NCBI_TaxID=266117 {ECO:0000313|EMBL:ABG04588.1, ECO:0000313|Proteomes:UP000006637};
RN [1] {ECO:0000313|EMBL:ABG04588.1, ECO:0000313|Proteomes:UP000006637}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9941 / NBRC 16129 / PRD-1
RC {ECO:0000313|Proteomes:UP000006637};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., da Costa M.S.,
RA Rainey F.A., Empadinhas N., Jolivet E., Battista J.R., Richardson P.;
RT "Complete sequence of Rubrobacter xylanophilus DSM 9941.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
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DR EMBL; CP000386; ABG04588.1; -; Genomic_DNA.
DR RefSeq; WP_011564605.1; NC_008148.1.
DR AlphaFoldDB; Q1AVJ0; -.
DR STRING; 266117.Rxyl_1627; -.
DR KEGG; rxy:Rxyl_1627; -.
DR eggNOG; COG1009; Bacteria.
DR HOGENOM; CLU_007100_6_0_11; -.
DR OrthoDB; 9811798at2; -.
DR PhylomeDB; Q1AVJ0; -.
DR Proteomes; UP000006637; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR Gene3D; 1.20.5.2700; -; 1.
DR InterPro; IPR018393; NADHpl_OxRdtase_5_subgr.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR003945; NU5C-like.
DR InterPro; IPR001516; Proton_antipo_N.
DR NCBIfam; TIGR01974; NDH_I_L; 1.
DR PANTHER; PTHR42829; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5; 1.
DR PANTHER; PTHR42829:SF2; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
DR PRINTS; PR01435; NPOXDRDTASE5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:ABG04588.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006637};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..630
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 70..121
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 137..425
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 656 AA; 70488 MW; 34F904B4AAAA768E CRC64;
MQSLGQQLVI AAIPVIPLVV FFVLALFGRL LRENAQYVAI FGMVFSVVFS FFALYLVIRD
GRPLEFSVYW INLGEGGGFP IGVYIDELAA VMLVVVSFVS LMIQLYSGGF MAGDRRFAWY
YAVLNLFTAS MLGLVVAPNF IELYICWELV GLCSYLLIGH WFEKPAARDA ALKAFIVTRI
GDAALFVGII MFWRATGTTA FEGIAEAAQA GFIGGSLLTA AVVLVFVGAI GKSAQFPLHV
WLPDAMEGPT PVSALIHAAT MVAAGVYLVA RTYDIFVQSP TAMLIVAYIG AFTAFMAATM
ALVKKDIKRV IAYSTVSQLG YMMLGLGVGA FSAGMFHLYN HAFFKALLFL CAGSIIHAMD
SYNLFEMGGL RRRMPLTFWT MVIAGLSLAG IFPLAGFWSK DAIIASAFEE HYYVLYALAI
GTVFLTAFYI FRAIFLAFTG EPRTEGAARA VESPGVMTVP MVILAVLSVA SGWVGIPEGF
GLPVRDYFGG FVAPSGFARE TLEVEPHGFS FLLAAISVLV GLAGIGLAYA MYVARPALAP
AMARRLFGLH TFLDKGWYFD ALYGATFVRA AFAVGRAVQG FDREVLGGLV GGIARGTGRL
GEALRRVQTG RVQNYALFIV VSVLVLAIVA GAQYAVIVAA LIALVTLATL AVGARL
//
