ID Q1AXU5_RUBXD Unreviewed; 386 AA.
AC Q1AXU5;
DT 11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=IMP dehydrogenase related 2 {ECO:0000313|EMBL:ABG03783.1};
GN OrderedLocusNames=Rxyl_0815 {ECO:0000313|EMBL:ABG03783.1};
OS Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1).
OC Bacteria; Actinomycetota; Rubrobacteria; Rubrobacterales; Rubrobacteraceae;
OC Rubrobacter.
OX NCBI_TaxID=266117 {ECO:0000313|EMBL:ABG03783.1, ECO:0000313|Proteomes:UP000006637};
RN [1] {ECO:0000313|EMBL:ABG03783.1, ECO:0000313|Proteomes:UP000006637}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9941 / NBRC 16129 / PRD-1
RC {ECO:0000313|Proteomes:UP000006637};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., da Costa M.S.,
RA Rainey F.A., Empadinhas N., Jolivet E., Battista J.R., Richardson P.;
RT "Complete sequence of Rubrobacter xylanophilus DSM 9941.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
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DR EMBL; CP000386; ABG03783.1; -; Genomic_DNA.
DR RefSeq; WP_011563801.1; NC_008148.1.
DR AlphaFoldDB; Q1AXU5; -.
DR STRING; 266117.Rxyl_0815; -.
DR KEGG; rxy:Rxyl_0815; -.
DR eggNOG; COG0516; Bacteria.
DR HOGENOM; CLU_064068_0_0_11; -.
DR OrthoDB; 9805398at2; -.
DR PhylomeDB; Q1AXU5; -.
DR Proteomes; UP000006637; Chromosome.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd00381; IMPDH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF85; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006637}.
FT DOMAIN 15..296
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 386 AA; 40927 MW; A06C426344D2F236 CRC64;
MDIEIGKGKT ARRAYGLDEI AIVPSRRTRD PEDVDISWNL GDLHLDLPCL ASALDAAVDP
TTAGIIGELG GLAVLNLEGI QTRYEDPEPV FEEIASLPQE KATRVMQEIY SEPVKEELIF
RRVQEIKDKG VIAAASLTPQ RVERYHRAAI EAGLDVLVIQ GTVVSAEHVS RQAKPLNLME
FIPSLNVPVV VGGCASYSTA LHLMRTGAVG VLVGVGPGRI CTTRGVLGVG VPQATAIADA
AAARTRHYME TGQYVNVIAD GGMRTGGDIA KAIACGADAV MLGSAFARAE EAPGKGYSWG
MATFHPTLPR GTRIKTGTVG TIEEILLGPA HENDGTLNLM GALRTSMATT GYQNIKEFQK
AEVMVAPALA TEGKLEQFSQ GVGMGR
//
