ID Q1D2C7_MYXXD Unreviewed; 737 AA.
AC Q1D2C7;
DT 11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 129.
DE SubName: Full=Sigma-54 dependent transcriptional regulator, Fis family {ECO:0000313|EMBL:ABF92785.1};
GN OrderedLocusNames=MXAN_5041 {ECO:0000313|EMBL:ABF92785.1};
OS Myxococcus xanthus (strain DK1622).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=246197 {ECO:0000313|EMBL:ABF92785.1, ECO:0000313|Proteomes:UP000002402};
RN [1] {ECO:0000313|EMBL:ABF92785.1, ECO:0000313|Proteomes:UP000002402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DK1622 {ECO:0000313|Proteomes:UP000002402};
RX PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S.,
RA Eisen J.A., Ronning C.M., Barbazuk W.B., Blanchard M., Field C.,
RA Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R.,
RA Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R.,
RA Kaplan H.B.;
RT "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
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DR EMBL; CP000113; ABF92785.1; -; Genomic_DNA.
DR AlphaFoldDB; Q1D2C7; -.
DR STRING; 246197.MXAN_5041; -.
DR EnsemblBacteria; ABF92785; ABF92785; MXAN_5041.
DR KEGG; mxa:MXAN_5041; -.
DR eggNOG; COG3284; Bacteria.
DR HOGENOM; CLU_000445_8_12_7; -.
DR Proteomes; UP000002402; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071:SF95; TRANSCRIPTIONAL REGULATORY PROTEIN ZRAR; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002402};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 408..637
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT REGION 362..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..678
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 77097 MW; C108ABFC2079A6EB CRC64;
MRGDPYLVMR RIRLGQEHCG VPRLLPPSGF NQDSRSLGTL TLSASPLLWE QFLVGALDGE
AGLRPELRSI LPRWQRSRSL GAPSTGQPDE GPRVGSLALV ERRARLEPVW HELGGMLEML
SAAPLPSGRV ALLADREGVI LATRSSGGDF THHADYVRLV EGACWDETSR GTNAIGTALA
ESSAVAVVGP AHYAQRHHGL VCYAAPVHDP FGELVAVLDV TGPAGAADPL VLVAVASVAH
AAEARLREVA WARVAAAARG GLESRLSRED GPVLVVEPMG RVSRFNAAAR ALLGGQGPMA
VEAALGVSWR VLTDAAFRGA ALETRLASQG PAWRIHAEAV GTGDASSALA VLVRLESSGV
RSLGMTPGSA DSRPTVAEPS TEGRGPRALS RDLWGADTVV PPGPWAALKG NDPQHRATLR
EAERFAPTSL PVLLLSETGT GKELLARALH SASTVATGPF VAVNCGALSP ALLESELFGH
APGAFTGARV GGAEGKLAAA DGGTLFLDEL AEMPPALQVL LLRVLEDGAY SRVGESRVRR
SRFRLVGATC RDLDAAVRNG TFRSDLYFRL QGAVLRLPPL RERNDLPELA HALLRRLSEE
EGLATSSISA AALTRLAAHP WPGNVRELKT VLRLALVRAG GAPVLDVDAL PSGLGSPLSP
GAQGEPRPAV PPVSSPPSQP SAGAAGGPLR ELEARAIQEA LALSGGNVAQ AARRLGIARS
TLYRMAERFG ITLPSRA
//
