ID Q1D5Z8_MYXXD Unreviewed; 324 AA.
AC Q1D5Z8;
DT 11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE RecName: Full=Fructose-bisphosphate aldolase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=MXAN_3743 {ECO:0000313|EMBL:ABF91345.1};
OS Myxococcus xanthus (strain DK1622).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=246197 {ECO:0000313|EMBL:ABF91345.1, ECO:0000313|Proteomes:UP000002402};
RN [1] {ECO:0000313|EMBL:ABF91345.1, ECO:0000313|Proteomes:UP000002402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DK1622 {ECO:0000313|Proteomes:UP000002402};
RX PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S.,
RA Eisen J.A., Ronning C.M., Barbazuk W.B., Blanchard M., Field C.,
RA Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R.,
RA Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R.,
RA Kaplan H.B.;
RT "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
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DR EMBL; CP000113; ABF91345.1; -; Genomic_DNA.
DR AlphaFoldDB; Q1D5Z8; -.
DR STRING; 246197.MXAN_3743; -.
DR EnsemblBacteria; ABF91345; ABF91345; MXAN_3743.
DR KEGG; mxa:MXAN_3743; -.
DR eggNOG; COG1830; Bacteria.
DR HOGENOM; CLU_057069_0_0_7; -.
DR Proteomes; UP000002402; Chromosome.
DR GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:InterPro.
DR CDD; cd00958; DhnA; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR InterPro; IPR041720; FbaB-like.
DR PANTHER; PTHR47916:SF1; 3-HYDROXY-5-PHOSPHONOOXYPENTANE-2,4-DIONE THIOLASE-RELATED; 1.
DR PANTHER; PTHR47916; FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1; 1.
DR Pfam; PF01791; DeoC; 1.
DR PIRSF; PIRSF038992; Aldolase_Ia; 1.
DR SMART; SM01133; DeoC; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002402}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 190
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
FT ACT_SITE 222
FT /note="Schiff-base intermediate with dihydroxyacetone-P"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
SQ SEQUENCE 324 AA; 34469 MW; 5C7D364CC921DB15 CRC64;
MAHAADCDCS RDRGSPHMPH TDRVKQILSW YPSDNPGTLT NLARLLNSGT LAGTGKLVIL
PVDQGFEHGP ARSFGPNPAG YDPDYHINLA IESGCNAYAA PLGFLEAVAG RYAGEIPLIL
KVNNSDTLAK VANPMSAVTS SVKDAVRLGC TAVGYTIYPG SGARNEQYED LRDIIAEAKS
YGLPTVLWAY PRGNLSKEGE TGIDVVAYAA QISAQLGAHV IKVKPPQDHI EQAEAKKAFE
KAGIPTKTLA DRVREVVRSA FNGKRIVIFS GGEAKGTDAL LEEIKQINAG GGFGSIMGRN
AFQRPHGESI KLLKDVMAIF AGKA
//
