ID Q1D9E1_MYXXD Unreviewed; 605 AA.
AC Q1D9E1;
DT 11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE RecName: Full=protein-secreting ATPase {ECO:0000256|ARBA:ARBA00024382};
DE EC=7.4.2.8 {ECO:0000256|ARBA:ARBA00024382};
GN Name=gspE {ECO:0000313|EMBL:ABF92256.1};
GN OrderedLocusNames=MXAN_2513 {ECO:0000313|EMBL:ABF92256.1};
OS Myxococcus xanthus (strain DK1622).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=246197 {ECO:0000313|EMBL:ABF92256.1, ECO:0000313|Proteomes:UP000002402};
RN [1] {ECO:0000313|EMBL:ABF92256.1, ECO:0000313|Proteomes:UP000002402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DK1622 {ECO:0000313|Proteomes:UP000002402};
RX PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S.,
RA Eisen J.A., Ronning C.M., Barbazuk W.B., Blanchard M., Field C.,
RA Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R.,
RA Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R.,
RA Kaplan H.B.;
RT "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + cellular proteinSide 1 = ADP + phosphate +
CC cellular proteinSide 2.; EC=7.4.2.8;
CC Evidence={ECO:0000256|ARBA:ARBA00034006};
CC -!- SIMILARITY: Belongs to the GSP E family.
CC {ECO:0000256|ARBA:ARBA00006611}.
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DR EMBL; CP000113; ABF92256.1; -; Genomic_DNA.
DR RefSeq; WP_011552584.1; NC_008095.1.
DR AlphaFoldDB; Q1D9E1; -.
DR STRING; 246197.MXAN_2513; -.
DR EnsemblBacteria; ABF92256; ABF92256; MXAN_2513.
DR GeneID; 41359890; -.
DR KEGG; mxa:MXAN_2513; -.
DR eggNOG; COG2804; Bacteria.
DR HOGENOM; CLU_013446_10_3_7; -.
DR OrthoDB; 9805147at2; -.
DR Proteomes; UP000002402; Chromosome.
DR GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR CDD; cd01129; PulE-GspE-like; 1.
DR Gene3D; 3.30.450.90; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.300.160; Type II secretion system, protein E, N-terminal domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001482; T2SS/T4SS_dom.
DR InterPro; IPR037257; T2SS_E_N_sf.
DR InterPro; IPR013369; T2SS_GspE.
DR InterPro; IPR007831; T2SS_GspE_N.
DR NCBIfam; TIGR02533; type_II_gspE; 1.
DR PANTHER; PTHR30258:SF2; BACTERIOPHAGE ADSORPTION PROTEIN B; 1.
DR PANTHER; PTHR30258; TYPE II SECRETION SYSTEM PROTEIN GSPE-RELATED; 1.
DR Pfam; PF05157; MshEN; 1.
DR Pfam; PF00437; T2SSE; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF160246; EspE N-terminal domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00662; T2SP_E; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002402};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 417..431
FT /note="Bacterial type II secretion system protein E"
FT /evidence="ECO:0000259|PROSITE:PS00662"
SQ SEQUENCE 605 AA; 65970 MW; FFA04BFB6038CEE7 CRC64;
MNLTADPALT SAATGGTVSP RNDATQLVAH GQAYLCGRPL GEILRAIVPS LTEEKLQEAL
AIQDEKGQRI GEALVGMKAV SEEDVAKALG HQLDLPYLAR IFAEEVDAEL VKRIPINFAK
QSRILPLSLE GDTVAVAVAD PLDTAALDHV RVLLGQSVSQ RIALGSTITD AINSVYDRSV
NETEQLVDEM ETQDLDAIAH ELDEPKDLLD EDDEAPVIRL VNSVLFRAAK ERASDIHIEP
MERELLVRFR VDGVLQEVIK PPKRYQNAIV SRVKVMGQLN IAEKRLPQDG RIRIKLAGRD
IDIRLSTIPT SFGERIVMRL LDKTATLLDL AEIGMSQKTL ESMEAVIKRS HGIILVTGPT
GSGKTTTLYG ALSKINTPDL NILTVEDPVE YQLKGIGQMA ISPKIGLTFA QGLRSFLRQD
PDVIMVGEIR DKETAEIAIQ ASLTGHLVLS TVHTNDAAGA VTRLVDMGVE PFLVASSLTG
ILAQRLVRRV CPDCRVPFEP TDAELKELGH SVASFKQRYG VDRIYKASGC PSCNRNGYRG
RTGIYEFLPV DDDVRQLVLK NVDASTIKRS ATSKGMTTLL DDGARKIALG ETTIAEVLSI
TQEDM
//
