ID Q1DAN3_MYXXD Unreviewed; 568 AA.
AC Q1DAN3;
DT 11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=HAMP domain/HD domain protein {ECO:0000313|EMBL:ABF85902.1};
GN OrderedLocusNames=MXAN_2061 {ECO:0000313|EMBL:ABF85902.1};
OS Myxococcus xanthus (strain DK1622).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=246197 {ECO:0000313|EMBL:ABF85902.1, ECO:0000313|Proteomes:UP000002402};
RN [1] {ECO:0000313|EMBL:ABF85902.1, ECO:0000313|Proteomes:UP000002402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DK1622 {ECO:0000313|Proteomes:UP000002402};
RX PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S.,
RA Eisen J.A., Ronning C.M., Barbazuk W.B., Blanchard M., Field C.,
RA Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R.,
RA Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R.,
RA Kaplan H.B.;
RT "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000113; ABF85902.1; -; Genomic_DNA.
DR RefSeq; WP_011552145.1; NC_008095.1.
DR AlphaFoldDB; Q1DAN3; -.
DR SMR; Q1DAN3; -.
DR STRING; 246197.MXAN_2061; -.
DR EnsemblBacteria; ABF85902; ABF85902; MXAN_2061.
DR GeneID; 41359470; -.
DR KEGG; mxa:MXAN_2061; -.
DR eggNOG; COG3437; Bacteria.
DR HOGENOM; CLU_034449_0_0_7; -.
DR OrthoDB; 9764337at2; -.
DR Proteomes; UP000002402; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00077; HDc; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF13487; HD_5; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002402};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 306..358
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 367..562
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 568 AA; 62234 MW; 64DF6DE9C10ED1DB CRC64;
MRLFKAILLL MLVVGVVPTL MVGWLSVSHT RELLVRDAQE LAQERVKQLR LKAEIFLGEP
TDAVLGLARV PGFFGLPLEA QQTHLASVLN QRRDVLALTV FDANRQRLPG LQAFSKHDVP
PTALAGHEER ARALLENIEG VRYADVVKDP QGSEPVLTLA FPLGEPVRGY IAADLSLADL
RKMLEQERVG STGFAYLADR HGHLVAGGGG VAGLGEDVAQ RGPVAHLLKQ LVGKSDMELF
HVGNFGEGRD AVVAAYTVLP ETGWAIVSEQ PVEHAYRQVD TMEQRILLGL GAAILVAVVL
AALFSRNLTR PLKGFISGAL ELAHGKFGVE VDIKQKNELG ELAQTFNYMS KQLLAYDMEN
RGLYESLEKG YLETIVALAN SIDSKDAYTR GHSQRVGDVS VQIGREMKLT ERELRQLQYG
GILHDIGKIG IVESILCKQT RLTDQEMDIM REHPAIGDAI IGPVSFLGAV RACVRHHHER
WDGTGYPDKL KGEDIPLLAR IVACADTFDA CTSTRPYQKA MPLEKAMEIL DNLSGAQLDP
KVVQALKQVL AKQGVRLEGH RLPVKLAS
//
