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Database: UniProt
Entry: Q1DDP1_MYXXD
LinkDB: Q1DDP1_MYXXD
Original site: Q1DDP1_MYXXD 
ID   Q1DDP1_MYXXD            Unreviewed;       824 AA.
AC   Q1DDP1;
DT   11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2006, sequence version 1.
DT   03-JUL-2019, entry version 88.
DE   SubName: Full=Aspartate kinase/homoserine dehydrogenase {ECO:0000313|EMBL:ABF92059.1};
DE            EC=1.1.1.3 {ECO:0000313|EMBL:ABF92059.1};
DE            EC=2.7.2.4 {ECO:0000313|EMBL:ABF92059.1};
GN   OrderedLocusNames=MXAN_0971 {ECO:0000313|EMBL:ABF92059.1};
OS   Myxococcus xanthus (strain DK 1622).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=246197 {ECO:0000313|EMBL:ABF92059.1, ECO:0000313|Proteomes:UP000002402};
RN   [1] {ECO:0000313|EMBL:ABF92059.1, ECO:0000313|Proteomes:UP000002402}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DK 1622 {ECO:0000313|EMBL:ABF92059.1,
RC   ECO:0000313|Proteomes:UP000002402};
RX   PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA   Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S.,
RA   Eisen J., Ronning C.M., Barbazuk W.B., Blanchard M., Field C.,
RA   Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R.,
RA   Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R.,
RA   Kaplan H.B.;
RT   "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
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DR   EMBL; CP000113; ABF92059.1; -; Genomic_DNA.
DR   STRING; 246197.MXAN_0971; -.
DR   EnsemblBacteria; ABF92059; ABF92059; MXAN_0971.
DR   KEGG; mxa:MXAN_0971; -.
DR   eggNOG; COG0460; LUCA.
DR   eggNOG; COG0527; LUCA.
DR   HOGENOM; HOG000271593; -.
DR   KO; K12524; -.
DR   OMA; YTHVDGI; -.
DR   Proteomes; UP000002402; Chromosome.
DR   GO; GO:0004072; F:aspartate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004412; F:homoserine dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0009067; P:aspartate family amino acid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.1160.10; -; 1.
DR   InterPro; IPR036393; AceGlu_kinase-like_sf.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR005106; Asp/hSer_DH_NAD-bd.
DR   InterPro; IPR001341; Asp_kinase.
DR   InterPro; IPR018042; Aspartate_kinase_CS.
DR   InterPro; IPR011147; Bifunc_aspartokin/hSer_DH.
DR   InterPro; IPR001342; HDH_cat.
DR   InterPro; IPR019811; HDH_CS.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00696; AA_kinase; 1.
DR   Pfam; PF00742; Homoserine_dh; 1.
DR   Pfam; PF03447; NAD_binding_3; 1.
DR   PIRSF; PIRSF000727; ThrA; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00657; asp_kinases; 1.
DR   PROSITE; PS00324; ASPARTOKINASE; 1.
DR   PROSITE; PS01042; HOMOSER_DHGENASE; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002402};
KW   Kinase {ECO:0000313|EMBL:ABF92059.1};
KW   Oxidoreductase {ECO:0000313|EMBL:ABF92059.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002402};
KW   Transferase {ECO:0000313|EMBL:ABF92059.1}.
FT   DOMAIN        2    281       AA_kinase. {ECO:0000259|Pfam:PF00696}.
FT   DOMAIN      469    606       NAD_binding_3. {ECO:0000259|Pfam:
FT                                PF03447}.
FT   DOMAIN      614    815       Homoserine_dh. {ECO:0000259|Pfam:
FT                                PF00742}.
SQ   SEQUENCE   824 AA;  87152 MW;  72C65A86E584FE5B CRC64;
     MMKFGGTSVG SPTRLRQVVE LIGKHARQGP LAVVVSAMGD TTDWLLDAAH LATEGDLEGA
     LAVATRIADL AKANAAALAP GQATALAERV DGLLAPLRQL LHGVSLTREC SAPTRDRVLS
     FGELVSATLL AELLTAHRTP ATFRDARQLL VTDDRFGAAR VDLVRTRERL QAARETWGVE
     VPVLPGFIAA TPDGRTTTLG RNGSDYTAAL VAQGLGASEV TVWTDVLGLH TADPELVTDA
     YPVAHLTHGE GLELAAVGAR MLHPRTMIPL IESGISLRIR NTMEPEHPGT LIDAIGSRDG
     QRPACIATRE DLALLGIEVR KLSDQFQLGE RVLAALREAR VTVWMTAQSA NGQSLAVVVP
     RPDAEHARSV LVTELAQELS RREVEPLEVR QPVTLLTLVA ETMGHGVNVA GRFFSALGAV
     GVNVRASAQG ASSRSLSCVV DAADTAVAAR TTHAAFNLAH QQVSLFVLGR GTVGGQLLAQ
     LRAQQALLRD RHGIALRVVG LADSKRALFD AAGLTLDGVE ARLEGVTPEA PQARTLVPLL
     DALRRLPVPI LVDCTAAGGL EALYTEAFQR GIHVVAANKK PLALPWEARE ALVDTARRNH
     VAYHYETTVA SSLPVIDTLA NLVRTGDTVR LITASLSGSL GFICNELTAG VPLSRAVRTA
     RERGFTEPDP REDLSGTDVA RKALILAREL GLPLSLSDVA LEPFVATDEC ASVDSFFQVL
     ATQDAAYAER VARCRHAGTV LRYLARIDPS KAGTGSPVIR VGPVGVEAGH PAADLRGSES
     FVSFTTTRHS DFPLTVRGAG AGGAVTASGV LADILRISQT LRGR
//
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