ID Q1GKB1_RUEST Unreviewed; 685 AA.
AC Q1GKB1;
DT 27-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 27-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:ABF62905.1};
GN OrderedLocusNames=TM1040_0172 {ECO:0000313|EMBL:ABF62905.1};
OS Ruegeria sp. (strain TM1040) (Silicibacter sp.).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Ruegeria.
OX NCBI_TaxID=292414 {ECO:0000313|EMBL:ABF62905.1, ECO:0000313|Proteomes:UP000000636};
RN [1] {ECO:0000313|Proteomes:UP000000636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TM1040 {ECO:0000313|Proteomes:UP000000636};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Brettin T., Bruce D., Han C., Tapia R., Goodwin L., Thompson L.S.,
RA Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA Belas R., Moran M.A., Buchan A., Gonzalez J.M., Schell M.A., Sun F.,
RA Richardson P.;
RT "Complete sequence of chromosome of Silicibacter sp. TM1040.";
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABF62905.1, ECO:0000313|Proteomes:UP000000636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TM1040 {ECO:0000313|EMBL:ABF62905.1,
RC ECO:0000313|Proteomes:UP000000636};
RX PubMed=17526795; DOI=10.1128/AEM.02580-06;
RA Moran M.A., Belas R., Schell M.A., Gonzalez J.M., Sun F., Sun S.,
RA Binder B.J., Edmonds J., Ye W., Orcutt B., Howard E.C., Meile C.,
RA Palefsky W., Goesmann A., Ren Q., Paulsen I., Ulrich L.E., Thompson L.S.,
RA Saunders E., Buchan A.;
RT "Ecological genomics of marine Roseobacters.";
RL Appl. Environ. Microbiol. 73:4559-4569(2007).
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DR EMBL; CP000377; ABF62905.1; -; Genomic_DNA.
DR RefSeq; WP_011537540.1; NC_008044.1.
DR AlphaFoldDB; Q1GKB1; -.
DR STRING; 292414.TM1040_0172; -.
DR KEGG; sit:TM1040_0172; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_49_5; -.
DR OrthoDB; 9814202at2; -.
DR Proteomes; UP000000636; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR005330; MHYT_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF03707; MHYT; 3.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50924; MHYT; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00244};
KW Reference proteome {ECO:0000313|Proteomes:UP000000636};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00244};
KW Transmembrane helix {ECO:0000256|PROSITE-ProRule:PRU00244}.
FT TRANSMEM 14..32
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 84..106
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 113..134
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 140..164
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 217..238
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT DOMAIN 12..200
FT /note="MHYT"
FT /evidence="ECO:0000259|PROSITE:PS50924"
FT DOMAIN 285..418
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 427..677
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 685 AA; 75144 MW; 3303B8D35C4E7CFF CRC64;
MYRLLDCITQ EHDYAFVAVA ALICVIGSLL SVHMSGRLTE WTGKRKIVQL PLAGLVTGAT
IWSTHFIAMT AYDPGYEHGY EPVLTATSLF VGVIGSFAAN ASLAFVPGRG APVLAGGLFG
LTVSAMHYTG MQAYLVPGTL YWNTGAVAAS VLLGVGLGAL SYVLMARPMR GIVGRLGPAL
VMVLAICLMH FTGMSAIEVL FDVAVDVPPK TISDNAMALL VFAVTAIILL IAMASASIEV
NMEDDARDQL NHAATHDPLT GMPNRMWLTR KLDALKIRLD ENETRRCAIM TIDLNLFKEV
NDVYGHSAGD AVLRCVALRM MQHEGEGECV TRVGGDEFVA IKEGFRRMEE VLSFAERLHA
AIVEPVDLED VSLRVGASIG IATTMDDGRD PADLLHKSDV AMYRAKSDPD TPICRFNAEM
DRRSREKTQI VHDLRLAVDN DEFELVYQLQ NALDTMEPVG FEVLLRWNHP KRGRVSPDVF
IPIAEETGLI RDIGHWVLRE ACREASLWRR PFSVAINVAP QQLVQPSFVE DVMDILMETG
LDPARLELEV TEASIIDDQA HTLKVMHKLK SIGIRIAMDD FGTGYSSLAT LQAFPFDKIK
IDRSFVQDVH KDAQRAAIVR STLLLGAALD IPVLAEGVEV EDELRFLRAE SCSSVQGFYF
GKPMPRDDMR AIACRDDGEA DVGVA
//
