ID Q1GUP4_SPHAL Unreviewed; 501 AA.
AC Q1GUP4;
DT 27-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 27-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ABF52628.1};
GN OrderedLocusNames=Sala_0910 {ECO:0000313|EMBL:ABF52628.1};
OS Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256)
OS (Sphingomonas alaskensis).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=317655 {ECO:0000313|EMBL:ABF52628.1, ECO:0000313|Proteomes:UP000006578};
RN [1] {ECO:0000313|EMBL:ABF52628.1, ECO:0000313|Proteomes:UP000006578}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13593 / LMG 18877 / RB2256
RC {ECO:0000313|Proteomes:UP000006578};
RX PubMed=19805210; DOI=10.1073/pnas.0903507106;
RA Lauro F.M., McDougald D., Thomas T., Williams T.J., Egan S., Rice S.,
RA DeMaere M.Z., Ting L., Ertan H., Johnson J., Ferriera S., Lapidus A.,
RA Anderson I., Kyrpides N., Munk A.C., Detter C., Han C.S., Brown M.V.,
RA Robb F.T., Kjelleberg S., Cavicchioli R.;
RT "The genomic basis of trophic strategy in marine bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:15527-15533(2009).
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DR EMBL; CP000356; ABF52628.1; -; Genomic_DNA.
DR RefSeq; WP_011541216.1; NC_008048.1.
DR AlphaFoldDB; Q1GUP4; -.
DR STRING; 317655.Sala_0910; -.
DR KEGG; sal:Sala_0910; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_0_5; -.
DR OrthoDB; 7056261at2; -.
DR Proteomes; UP000006578; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ABF52628.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006578}.
FT DOMAIN 10..364
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 410..484
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 501 AA; 53244 MW; 0F0BF549535D2D12 CRC64;
MRTSLLLDIA ADAASDRPAL GSGEEAIDFG TYRARASQTA AWLASRGKAN TAFLGMNGEL
LPILLFASGM AGTAFVPLNY RLPDADLNRL VARTAPAVLI ADDDMLARIA PAEGIELVAR
SDFEAEFLAG PTPPPAALPE AENDIAVLLF TSGTTGEPKA AVLRHTNLTA YVMSTVEFLG
AGEDEAALVS VPSYHVAGIS AILTAAYGGR RIVYLPAFTP DQWVATAAAE AVTHAMVVPT
MLDRILDVME QTGETLPALR ALSYGGGKMP EPVIARALAK LPHVDFVNAY GLTETSSTIA
LLGAEDHRIA FASGDPAIRR RIASVGKPLP SIELEIRRED GTPCAPGEHG EIHVRGEQVS
GEYLNKKAVA DDGWFATNDA GWLDEGGYLF VEGRLDDVIV RGGENISPGE IEDLLRTHDD
IADCAVLGIP CEKWGEKVVA VIVSRSGRPD IEALSSAIRA KLRSTKTPEQ WFVRDALPYN
ETGKLLRRVL KAELAEAACA G
//
