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Database: UniProt
Entry: Q1I8W6_PSEE4
LinkDB: Q1I8W6_PSEE4
Original site: Q1I8W6_PSEE4 
ID   Q1I8W6_PSEE4            Unreviewed;       353 AA.
AC   Q1I8W6;
DT   13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2006, sequence version 1.
DT   08-MAY-2019, entry version 87.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   Name=aroF-2 {ECO:0000313|EMBL:CAK15912.1};
GN   OrderedLocusNames=PSEEN3146 {ECO:0000313|EMBL:CAK15912.1};
OS   Pseudomonas entomophila (strain L48).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=384676 {ECO:0000313|EMBL:CAK15912.1, ECO:0000313|Proteomes:UP000000658};
RN   [1] {ECO:0000313|EMBL:CAK15912.1, ECO:0000313|Proteomes:UP000000658}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L48 {ECO:0000313|EMBL:CAK15912.1,
RC   ECO:0000313|Proteomes:UP000000658};
RX   PubMed=16699499; DOI=10.1038/nbt1212;
RA   Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C.,
RA   Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B.,
RA   Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F.;
RT   "Complete genome sequence of the entomopathogenic and metabolically
RT   versatile soil bacterium Pseudomonas entomophila.";
RL   Nat. Biotechnol. 24:673-679(2006).
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; CT573326; CAK15912.1; -; Genomic_DNA.
DR   RefSeq; WP_011534300.1; NC_008027.1.
DR   STRING; 384676.PSEEN3146; -.
DR   EnsemblBacteria; CAK15912; CAK15912; PSEEN3146.
DR   GeneID; 32806251; -.
DR   KEGG; pen:PSEEN3146; -.
DR   eggNOG; ENOG4105E99; Bacteria.
DR   eggNOG; COG0722; LUCA.
DR   HOGENOM; HOG000220501; -.
DR   KO; K01626; -.
DR   OMA; PCLSWED; -.
DR   OrthoDB; 853329at2; -.
DR   BioCyc; PENT384676:PSEEN_RS14560-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000000658; Chromosome.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000658};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:CAK15912.1}.
FT   DOMAIN       52    346       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   353 AA;  37892 MW;  77038EA8C1F82012 CRC64;
     MQATNLALPL TQPQAANSTV SQRLPSPHLL KQQMPLPTEL AQQVQAHRQA IRAILEGRDE
     RLLVVVGPCS LHDPRSALEY ADRLAALSRE VDDKLLLVMR AYVEKPRTTV GWKGLAYDPH
     LDGSDDMHAG IALSRGLMLS MIERGLPIAT ELLQPMAAGY FDDLLGWAAI GARTTESQIH
     REMVSGLELP VGFKNGTDGG IGIACDAMRS AAHPHRHFGM DAQGYPAIIE TLGNPDTHLV
     LRGGHKGPNY DATSIAQARQ GLAKAGLQAR IMVDCSHANS GKDPARQPAV FEEVLAQRLG
     GDRSIVGVML EGHLFDGCQA LGKGVLKYGV SITDGCLGWS STEAMLREAA GRL
//
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