ID Q1I9B7_PSEE4 Unreviewed; 680 AA.
AC Q1I9B7;
DT 13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=PSEEN2989 {ECO:0000313|EMBL:CAK15761.1};
OS Pseudomonas entomophila (strain L48).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=384676 {ECO:0000313|EMBL:CAK15761.1, ECO:0000313|Proteomes:UP000000658};
RN [1] {ECO:0000313|EMBL:CAK15761.1, ECO:0000313|Proteomes:UP000000658}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L48 {ECO:0000313|EMBL:CAK15761.1,
RC ECO:0000313|Proteomes:UP000000658};
RX PubMed=16699499; DOI=10.1038/nbt1212;
RA Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C.,
RA Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P.,
RA Weissenbach J., Lemaitre B., Medigue C., Boccard F.;
RT "Complete genome sequence of the entomopathogenic and metabolically
RT versatile soil bacterium Pseudomonas entomophila.";
RL Nat. Biotechnol. 24:673-679(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CT573326; CAK15761.1; -; Genomic_DNA.
DR RefSeq; WP_011534149.1; NC_008027.1.
DR AlphaFoldDB; Q1I9B7; -.
DR STRING; 384676.PSEEN2989; -.
DR GeneID; 32806106; -.
DR KEGG; pen:PSEEN2989; -.
DR eggNOG; COG4191; Bacteria.
DR HOGENOM; CLU_000445_114_51_6; -.
DR OrthoDB; 9770473at2; -.
DR Proteomes; UP000000658; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 2.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CAK15761.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000313|EMBL:CAK15761.1}.
FT DOMAIN 315..539
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 561..677
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 611
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 680 AA; 74581 MW; E04DF5704CA44C67 CRC64;
MPERELHELR QRNAELEAQL AQLQGIDNSL YRFLFDTMDE GFCVIEFFDG PHGPLSDYIH
VIANAAYARH AGIPNVVGQK LREMVPDEAD DWVARYGEVL RTGQPLQFEQ ELVATGRVLS
VTTFRIEPAE RNQVAVLFKD VTEKRRAETA LQQLNDHLEQ RVVAALAERR LFAELVERSV
ARVQVLDTSL CFLAVNARAV KDFEFLFGRS VKAGDSLVEC LSGFPEECER SVTLWRRALA
GESFIEVIQY GRGERQRHFE LRFNPLRDAS DAIVGAYLFV YDISRQVSEQ QRLLEAEDAL
RQAQKMEAVG QLTGGIAHDF NNLLGGILGA QELVRQRLEQ ARLDDIPALL DTAGDSARRA
AALVHRLLAF SRRQTLLPQA TSVGALILDI EELIRRSVGP AIAVHVGCAP GLWSTFIDPP
QLESALLNLC INARDALPDG GRIEIRCENL SLDTERATAL DLAAGEYLQL SVEDNGRGMP
AEVVERAIDP FFTTKPLGQG TGLGLSMAFG FVRQSGGQLQ IQSTPGAGTR IDLYLPRHPE
APKAPEARPV AERLAHPGRA RILLVEDQAA LRLVIGEVLD EFGHDVEGVE HGPAALALLA
HGFVPDLLIS DIGLPGGLNG RQVAEACRAR HPDLPVLFIT GYDESAALSD GQLPARTAVL
RKPFELPAIA DLVAQLLSAG
//
