ID Q1J402_SPHAL Unreviewed; 495 AA.
AC Q1J402;
DT 13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ABF54921.1};
GN OrderedLocusNames=Sala_3218 {ECO:0000313|EMBL:ABF54921.1};
OS Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256)
OS (Sphingomonas alaskensis).
OG Plasmid F {ECO:0000313|Proteomes:UP000006578}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=317655 {ECO:0000313|EMBL:ABF54921.1, ECO:0000313|Proteomes:UP000006578};
RN [1] {ECO:0000313|EMBL:ABF54921.1, ECO:0000313|Proteomes:UP000006578}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13593 / LMG 18877 / RB2256
RC {ECO:0000313|Proteomes:UP000006578};
RC PLASMID=Plasmid F {ECO:0000313|Proteomes:UP000006578};
RX PubMed=19805210; DOI=10.1073/pnas.0903507106;
RA Lauro F.M., McDougald D., Thomas T., Williams T.J., Egan S., Rice S.,
RA DeMaere M.Z., Ting L., Ertan H., Johnson J., Ferriera S., Lapidus A.,
RA Anderson I., Kyrpides N., Munk A.C., Detter C., Han C.S., Brown M.V.,
RA Robb F.T., Kjelleberg S., Cavicchioli R.;
RT "The genomic basis of trophic strategy in marine bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:15527-15533(2009).
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DR EMBL; CP000357; ABF54921.1; -; Genomic_DNA.
DR RefSeq; WP_011536545.1; NC_008036.1.
DR AlphaFoldDB; Q1J402; -.
DR KEGG; sal:Sala_3218; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_0_5; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000006578; Plasmid F.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ABF54921.1};
KW Plasmid {ECO:0000313|EMBL:ABF54921.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006578}.
FT DOMAIN 12..339
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 399..474
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 495 AA; 53869 MW; E99B8E07AEC642D1 CRC64;
MEVRRISDAL KVRAQHQADE IAHDDTRRQI SFAEWDREVD EVAGGLAAAG LVPGDRVFLP
ISNFHAVEMA IAVFAVFRAG GIACPINTRL NPKEIAEYAA LCEPRFCITD APDRVRDLKL
AACWHAEDMP RNLTALPDQA SLDPGADAEI LATSGTTGKI KGVVISHPDL MTGVTGYNMD
RSRSTLNALP LTGSGGNIGI VMLPARGGAT AITQPKFDPK GFLDLVREKR PNLVYLVPSM
LRLVLDHPDA PDYDFSGVKY LMTGTAPLPH DSVKRAMDLW PHLRIRNSYG MSEGGVGVST
TSAEQVLKPG CVGKLPKHMQ LRDEAGNVIT TVGVVGEIYG WQKHPRRYWN DEQATADSFR
GGWTKTGDLG FIDEDGDLIM AGRSKELIIR GGYNITPLEI ETVLHLHPAV QQAAVVGIPH
EILGEDIAAA VTLRPGKTAE TEEILSFCRE HLADNKVPRT LVIMDSLPLN PNGKILKKYL
AEPLARAAEA RRRAA
//
