ID Q1L882_DANRE Unreviewed; 347 AA.
AC Q1L882; A0A8M1ND64;
DT 30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 30-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Novel protein {ECO:0000313|EMBL:CAK04863.1};
DE SubName: Full=Si:ch211-244b2.3 {ECO:0000313|Ensembl:ENSDARP00000091384};
GN Name=si:ch211-244b2.3 {ECO:0000313|Ensembl:ENSDARP00000091384,
GN ECO:0000313|RefSeq:NP_001076279.1,
GN ECO:0000313|ZFIN:ZDB-GENE-030131-4737};
GN Synonyms=fd56h10 {ECO:0000313|RefSeq:NP_001076279.1}, si:ch211-244b2.2
GN {ECO:0000313|RefSeq:NP_001076279.1}, wu:fd56h10
GN {ECO:0000313|RefSeq:NP_001076279.1};
GN ORFNames=CH211-265O23.3-001 {ECO:0000313|EMBL:CAK04863.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:CAK04863.1};
RN [1] {ECO:0000313|RefSeq:NP_001076279.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12477932; DOI=10.1073/pnas.242603899;
RG Mammalian Gene Collection Program Team;
RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D.,
RA Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F.,
RA Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H.,
RA Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K.,
RA Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F.,
RA Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S.,
RA Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J.,
RA Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J.,
RA Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M.,
RA Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G.,
RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C.,
RA Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I.,
RA Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.;
RT "Generation and initial analysis of more than 15,000 full-length human and
RT mouse cDNA sequences.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002).
RN [2] {ECO:0000313|EMBL:CAK04863.1}
RP NUCLEOTIDE SEQUENCE.
RA Matthews L.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSDARP00000091384}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000091384};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
RN [4] {ECO:0000313|Ensembl:ENSDARP00000091384, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000091384};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [5] {ECO:0000313|RefSeq:NP_001076279.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26469318;
RA Elkon R., Milon B., Morrison L., Shah M., Vijayakumar S., Racherla M.,
RA Leitch C.C., Silipino L., Hadi S., Weiss-Gayet M., Barras E., Schmid C.D.,
RA Ait-Lounis A., Barnes A., Song Y., Eisenman D.J., Eliyahu E.,
RA Frolenkov G.I., Strome S.E., Durand B., Zaghloul N.A., Jones S.M.,
RA Reith W., Hertzano R.;
RT "RFX transcription factors are essential for hearing in mice.";
RL Nat. Commun. 6:8549-8549(2015).
RN [6] {ECO:0000313|RefSeq:NP_001076279.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ARTD/PARP family.
CC {ECO:0000256|ARBA:ARBA00024347}.
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DR EMBL; CR749747; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CR936411; CAK04863.1; -; Genomic_DNA.
DR RefSeq; NP_001076279.1; NM_001082810.1.
DR PaxDb; 7955-ENSDARP00000091384; -.
DR Ensembl; ENSDART00000100611.6; ENSDARP00000091384.3; ENSDARG00000069244.7.
DR GeneID; 557230; -.
DR KEGG; dre:557230; -.
DR AGR; ZFIN:ZDB-GENE-030131-4737; -.
DR ZFIN; ZDB-GENE-030131-4737; si:ch211-244b2.3.
DR eggNOG; ENOG502QPQ3; Eukaryota.
DR HOGENOM; CLU_821273_0_0_1; -.
DR OMA; DQLWCEY; -.
DR OrthoDB; 5322837at2759; -.
DR TreeFam; TF353140; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000000437; Chromosome 4.
DR Bgee; ENSDARG00000069244; Expressed in spleen and 20 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IBA:GO_Central.
DR GO; GO:1990404; F:NAD+-protein ADP-ribosyltransferase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.720.50; -; 3.
DR InterPro; IPR004170; WWE-dom.
DR InterPro; IPR018123; WWE-dom_subgr.
DR InterPro; IPR037197; WWE_dom_sf.
DR PANTHER; PTHR45740; POLY [ADP-RIBOSE] POLYMERASE; 1.
DR PANTHER; PTHR45740:SF2; POLY [ADP-RIBOSE] POLYMERASE; 1.
DR Pfam; PF02825; WWE; 3.
DR SMART; SM00678; WWE; 3.
DR SUPFAM; SSF117839; WWE domain; 3.
DR PROSITE; PS50918; WWE; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT DOMAIN 67..152
FT /note="WWE"
FT /evidence="ECO:0000259|PROSITE:PS50918"
FT DOMAIN 172..256
FT /note="WWE"
FT /evidence="ECO:0000259|PROSITE:PS50918"
FT DOMAIN 259..344
FT /note="WWE"
FT /evidence="ECO:0000259|PROSITE:PS50918"
SQ SEQUENCE 347 AA; 39791 MW; 472AC4249869FAC5 CRC64;
MATSNYYEWQ LFNGNQWVYI NNDFIIETHY CQPGASGIRI NLNTGAVYID FDEMTADGPD
DNLAIRRNTL LSQNQKQEVG WYYKDNHRWC EYGSQGWGGR TSSIGSDFIE QHFNSNPSGS
VQFTAGNMTY SVDFNAMTQT NLSTHLTRKV RRRPKFNKIV AINNSFLNSS PTLASPSTNP
SNSSSHFIWE FMGDEGIWTE YQKPACSLDS AEIERLYQLN PQCQVSFTAR RFSYTLYFGG
MYQVNDRLGT RRTVRRIASG SQQTNNALSQ ARWQFKDMDG KWKDYVRGGS RGKCSVSSQD
IEAQYQQDPT AIMSFSAGRF NYELDFSAMT QTNLRTNTRR AVQRLQQ
//
