ID Q1LC21_CUPMC Unreviewed; 484 AA.
AC Q1LC21;
DT 30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 30-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Transporter major facilitator superfamily (MFS) {ECO:0000313|EMBL:ABF12305.1};
GN OrderedLocusNames=Rmet_5446 {ECO:0000313|EMBL:ABF12305.1};
OS Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 /
OS CH34) (Ralstonia metallidurans).
OG Plasmid megaplasmid CH34 {ECO:0000313|Proteomes:UP000002429}.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=266264 {ECO:0000313|EMBL:ABF12305.1, ECO:0000313|Proteomes:UP000002429};
RN [1] {ECO:0000313|Proteomes:UP000002429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43123 / DSM 2839 / NBRC 102507 / CH34
RC {ECO:0000313|Proteomes:UP000002429};
RC PLASMID=Plasmid megaplasmid CH34 {ECO:0000313|Proteomes:UP000002429};
RX PubMed=20463976; DOI=10.1371/journal.pone.0010433;
RA Janssen P.J., Van Houdt R., Moors H., Monsieurs P., Morin N., Michaux A.,
RA Benotmane M.A., Leys N., Vallaeys T., Lapidus A., Monchy S., Medigue C.,
RA Taghavi S., McCorkle S., Dunn J., van der Lelie D., Mergeay M.;
RT "The complete genome sequence of Cupriavidus metallidurans strain CH34, a
RT master survivalist in harsh and anthropogenic environments.";
RL PLoS ONE 5:E10433-E10433(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000353; ABF12305.1; -; Genomic_DNA.
DR RefSeq; WP_011519852.1; NC_007974.2.
DR AlphaFoldDB; Q1LC21; -.
DR KEGG; rme:Rmet_5446; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_001265_46_6_4; -.
DR Proteomes; UP000002429; Plasmid megaplasmid CH34.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23508; CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR23508:SF10; CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:ABF12305.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002429};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..452
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 484 AA; 52232 MW; DFA60B8AE0FB60EE CRC64;
MQTSAIKIRG IDDVIAFIDS CPGIRGRAGV IWWLALGGLF LDAFSNSALS AGLGPMTRDL
KLEPAQVALL TSFASWVAIA FNPLGGWMAD RWGRVKPLIL AKVFAVVGAL LVVFAPDFNA
ILVGRFFVGA AYGIDFAIAM AVLAEFTPVK LKSRLNTWQG MWYTAVCLNL LLALLFYSWQ
VGDTIWRYSV AATAVFGVGI LILQVLFLVE SPTWLARKER LEAAAQAMTR IYGRPFEAAP
LAERVPVTNM ARRGLANVLL IFRGIYLPRT ILAATVQIGQ SIQYFGIGWY LPLISAALFG
KDFVYATIGA LVFNVCGIFG GFLSPVIGRK LGLRRASAYG FAAVFVMLLI LGLFNGKMPT
WVAVVVPSLF ILFHSGGPGA NGKSLSSLSF RSELRAGANG VIGALGAIGA ALGLLVFPLF
RARYGLETTF LILSVVPLVA SIICFLIRWD PTRTAIHPDN EADAPQFRSD ARDGAGFMHP
ATEK
//
