ID Q1LMQ3_CUPMC Unreviewed; 244 AA.
AC Q1LMQ3;
DT 30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 30-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=DNA-binding transcriptional dual regulator, global regulator of anaerobic growth {ECO:0000313|EMBL:ABF08573.1};
GN Name=fnr {ECO:0000313|EMBL:ABF08573.1};
GN OrderedLocusNames=Rmet_1692 {ECO:0000313|EMBL:ABF08573.1};
OS Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 /
OS CH34) (Ralstonia metallidurans).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=266264 {ECO:0000313|EMBL:ABF08573.1, ECO:0000313|Proteomes:UP000002429};
RN [1] {ECO:0000313|Proteomes:UP000002429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43123 / DSM 2839 / NBRC 102507 / CH34
RC {ECO:0000313|Proteomes:UP000002429};
RX PubMed=20463976; DOI=10.1371/journal.pone.0010433;
RA Janssen P.J., Van Houdt R., Moors H., Monsieurs P., Morin N., Michaux A.,
RA Benotmane M.A., Leys N., Vallaeys T., Lapidus A., Monchy S., Medigue C.,
RA Taghavi S., McCorkle S., Dunn J., van der Lelie D., Mergeay M.;
RT "The complete genome sequence of Cupriavidus metallidurans strain CH34, a
RT master survivalist in harsh and anthropogenic environments.";
RL PLoS ONE 5:E10433-E10433(2010).
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DR EMBL; CP000352; ABF08573.1; -; Genomic_DNA.
DR RefSeq; WP_011516423.1; NC_007973.1.
DR AlphaFoldDB; Q1LMQ3; -.
DR STRING; 266264.Rmet_1692; -.
DR KEGG; rme:Rmet_1692; -.
DR eggNOG; COG0664; Bacteria.
DR HOGENOM; CLU_075053_0_2_4; -.
DR Proteomes; UP000002429; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR CDD; cd00092; HTH_CRP; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR24567:SF75; FUMARATE AND NITRATE REDUCTION REGULATORY PROTEIN; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR PRINTS; PR00034; HTHCRP.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000313|EMBL:ABF08573.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002429}.
FT DOMAIN 14..116
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 148..221
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 244 AA; 26901 MW; 62155B0B98D8DCC7 CRC64;
MPRCSACTFA SFCLPGGLNR RDIDRLDSVV HGRISLHKGE SLYRLGDPVT SIYAIRVGTL
KSQVSTQDGR VQIVGFHLPG ELVGLDSLVS PQYMSHAVAL EDARLCRINL TALRDLAVAL
PGLYNNILRL MANEVRHDHA MLRTLGVLNA EERLIAFLLS LSARLSARGF AASEFQLRMT
REEIGSYLGL KLETISRLFS RLSETGLITV RHRSVKLNDL NGLRLIYEGS SGALASFQNH
CLAN
//
