ID ZNUC_RHIJ3 Reviewed; 303 AA.
AC Q1MEG2;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE RecName: Full=Zinc import ATP-binding protein ZnuC {ECO:0000255|HAMAP-Rule:MF_01725};
DE EC=7.2.2.20 {ECO:0000255|HAMAP-Rule:MF_01725};
GN Name=znuC {ECO:0000255|HAMAP-Rule:MF_01725}; OrderedLocusNames=RL3177;
OS Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium
OS leguminosarum bv. viciae).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium;
OC Rhizobium johnstonii.
OX NCBI_TaxID=216596;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 114642 / LMG 32736 / 3841;
RX PubMed=16640791; DOI=10.1186/gb-2006-7-4-r34;
RA Young J.P.W., Crossman L.C., Johnston A.W.B., Thomson N.R., Ghazoui Z.F.,
RA Hull K.H., Wexler M., Curson A.R.J., Todd J.D., Poole P.S., Mauchline T.H.,
RA East A.K., Quail M.A., Churcher C., Arrowsmith C., Cherevach I.,
RA Chillingworth T., Clarke K., Cronin A., Davis P., Fraser A., Hance Z.,
RA Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H.,
RA Rabbinowitsch E., Sanders M., Simmonds M., Whitehead S., Parkhill J.;
RT "The genome of Rhizobium leguminosarum has recognizable core and accessory
RT components.";
RL Genome Biol. 7:R34.1-R34.20(2006).
CC -!- FUNCTION: Part of the ABC transporter complex ZnuABC involved in zinc
CC import. Responsible for energy coupling to the transport system.
CC {ECO:0000255|HAMAP-Rule:MF_01725}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP(in) + H2O(in) + Zn(2+)(out) = ADP(in) + H(+)(in) +
CC phosphate(in) + Zn(2+)(in); Xref=Rhea:RHEA:29795, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:29105, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.2.2.20;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01725};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (ZnuC),
CC two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA).
CC {ECO:0000255|HAMAP-Rule:MF_01725}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01725}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01725}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Zinc importer
CC (TC 3.A.1.15.5) family. {ECO:0000255|HAMAP-Rule:MF_01725}.
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DR EMBL; AM236080; CAK08664.1; -; Genomic_DNA.
DR RefSeq; WP_011652682.1; NC_008380.1.
DR AlphaFoldDB; Q1MEG2; -.
DR SMR; Q1MEG2; -.
DR EnsemblBacteria; CAK08664; CAK08664; RL3177.
DR KEGG; rle:RL3177; -.
DR eggNOG; COG1121; Bacteria.
DR HOGENOM; CLU_000604_1_11_5; -.
DR Proteomes; UP000006575; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015633; F:ABC-type zinc transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42734; METAL TRANSPORT SYSTEM ATP-BINDING PROTEIN TM_0124-RELATED; 1.
DR PANTHER; PTHR42734:SF9; ZINC IMPORT ATP-BINDING PROTEIN ZNUC; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS51298; ZNUC; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW Nucleotide-binding; Translocase; Transport; Zinc; Zinc transport.
FT CHAIN 1..303
FT /note="Zinc import ATP-binding protein ZnuC"
FT /id="PRO_0000281536"
FT DOMAIN 17..232
FT /note="ABC transporter"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01725"
FT REGION 263..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 49..56
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01725"
SQ SEQUENCE 303 AA; 32818 MW; 0E1FC6ABE18373D8 CRC64;
MLSPAKTPAG IRAEPLVSLE NVGVLRNGRW LVRGVDFSVS RGEIVTLIGP NGSGKSTSAK
AAIGVLKPDE GRVERKAGLK VGYVPQKLSI DWTLPLSVRR LMTLTGPLPE RDMLSALESA
GIAHMLDAEV QHLSGGEFQR ALMARAIARK PDLLVLDEPV QGVDFSGEIV LYDLIKSIRN
ATGCGILLIS HDLHVVMAET DTVICLNGHV CCRGTPESVS RSPEYVRLFG SRAAQTLAVY
SHHHDHTHLP DGRVQHADGT VTDHCHPDDG HHAHEHGHAG HEHDHDHPDH AHPHAHEAGE
RHA
//
