ID Q1MNY5_LAWIP Unreviewed; 388 AA.
AC Q1MNY5;
DT 30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 30-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Na+/H+-dicarboxylate symporters {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=LIB020 {ECO:0000313|EMBL:CAJ53919.1};
OS Lawsonia intracellularis (strain PHE/MN1-00).
OG Plasmid pLaw2 {ECO:0000313|Proteomes:UP000002430}.
OC Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC Desulfovibrionaceae; Lawsonia.
OX NCBI_TaxID=363253 {ECO:0000313|EMBL:CAJ53919.1, ECO:0000313|Proteomes:UP000002430};
RN [1] {ECO:0000313|EMBL:CAJ53919.1, ECO:0000313|Proteomes:UP000002430}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHE/MN1-00 {ECO:0000313|EMBL:CAJ53919.1,
RC ECO:0000313|Proteomes:UP000002430};
RC PLASMID=pLaw2 {ECO:0000313|Proteomes:UP000002430};
RA Kaur K., Zhang Q., Beckler D., Munir S., Li L., Kinsley K., Herron L.,
RA Peterson A., May B., Singh S., Gebhart C., Kapur V.;
RT "The complete genome sequence of Lawsonia intracellularis: the causative
RT agent of proliferative enteropathy.";
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AM180254; CAJ53919.1; -; Genomic_DNA.
DR RefSeq; WP_011527315.1; NC_008013.1.
DR AlphaFoldDB; Q1MNY5; -.
DR KEGG; lip:LIB020; -.
DR eggNOG; COG1301; Bacteria.
DR HOGENOM; CLU_035303_0_0_7; -.
DR OrthoDB; 9768885at2; -.
DR Proteomes; UP000002430; Plasmid pLaw2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF9; INTEGRAL MEMBRANE TRANSPORT PROTEIN-RELATED; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:CAJ53919.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002430};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 388 AA; 43492 MW; E17B40ED0463C3DB CRC64;
MFRKMPFIMA IMIIFIVLLS PIIPLYIKQL LYSISLSIKS IILFILPFII FSLLFKASVI
LSRNATKVIG IIVVFVCCSN FLSTFISHYI GIWIYSSDLA KLQFHNIDNL TTLWLLHLPN
IISNSDAMIT GVILGIFAST FFPKKAEQLA VTIEIYIESF LNNFIFFVPL FVVGFVIKMQ
HDGILELLTK EYALIFSLIA ISQFTYIIIC YLLLNKFSFI RVFNNIKRVF PAVISGFSTM
SSAASMPLLI MGLESNTKNK DVVRAVVPAT INIHLIGDCF AIPILAYAIL KGFGIEEPSL
VTYIVFIFYF ILAKFSVVAV PGGGIIVMLP LLESYLGFNS EMLSLITALY ILFDPVITAA
NVLGNGAFAK LIDKMLSYMQ KTKYQLSI
//
