ID   Q1MP33_LAWIP            Unreviewed;       359 AA.
AC   Q1MP33;
DT   30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT   30-MAY-2006, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Integrase {ECO:0000313|EMBL:CAJ53924.1};
GN   OrderedLocusNames=LIA001 {ECO:0000313|EMBL:CAJ53924.1};
OS   Lawsonia intracellularis (strain PHE/MN1-00).
OG   Plasmid pLaw1 {ECO:0000313|Proteomes:UP000002430}.
OC   Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC   Desulfovibrionaceae; Lawsonia.
OX   NCBI_TaxID=363253 {ECO:0000313|EMBL:CAJ53924.1, ECO:0000313|Proteomes:UP000002430};
RN   [1] {ECO:0000313|EMBL:CAJ53924.1, ECO:0000313|Proteomes:UP000002430}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PHE/MN1-00 {ECO:0000313|EMBL:CAJ53924.1,
RC   ECO:0000313|Proteomes:UP000002430};
RC   PLASMID=pLaw1 {ECO:0000313|Proteomes:UP000002430};
RA   Kaur K., Zhang Q., Beckler D., Munir S., Li L., Kinsley K., Herron L.,
RA   Peterson A., May B., Singh S., Gebhart C., Kapur V.;
RT   "The complete genome sequence of Lawsonia intracellularis: the causative
RT   agent of proliferative enteropathy.";
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC       {ECO:0000256|ARBA:ARBA00008857}.
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DR   EMBL; AM180253; CAJ53924.1; -; Genomic_DNA.
DR   RefSeq; WP_011527267.1; NC_008012.1.
DR   AlphaFoldDB; Q1MP33; -.
DR   KEGG; lip:LIA001; -.
DR   HOGENOM; CLU_027562_17_7_7; -.
DR   OrthoDB; 5418320at2; -.
DR   Proteomes; UP000002430; Plasmid pLaw1.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   CDD; cd00796; INT_Rci_Hp1_C; 1.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR025269; SAM-like_dom.
DR   PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR   PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR   Pfam; PF13102; Phage_int_SAM_5; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Plasmid {ECO:0000313|EMBL:CAJ53924.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002430}.
FT   DOMAIN          172..349
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000259|PROSITE:PS51898"
SQ   SEQUENCE   359 AA;  41603 MW;  7BFD389B72257B67 CRC64;
     MAIRKRNLKS KNAISYQVYW NNPYTGLREA KTFPTLFEAS AFESLIKHRL KYEKTFFKPK
     ENTTLEPVTL YDAVLCYLQK KKFTPQYTKI ISCSLQSILT SYGDVKLSEL KTDFFVHLKN
     YLETKTKKNG ECFSRSYIHI QLSRLRTILN WAYEQGMLVM LPKMKLGDPY YTRTIPPTFD
     EITRLIAVSP PHLVRIIILG AAFGLRVGPS ELFSLTWDKI DLKSGVVRIS TSKKNPRFPW
     REVPIKDELK PFFSTWFEED TKNGLSYVIT YKGKPIRSIH SSWSKALKNA GITRRIRPYD
     LRHSFASELI SSGVDVGTVA QLLNHSSPNM LFKYYQYVET KQKKRAIELL PSVSCDITM
//