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Database: UniProt
Entry: Q1MTR1
LinkDB: Q1MTR1
Original site: Q1MTR1 
ID   IRC3_SCHPO              Reviewed;         606 AA.
AC   Q1MTR1;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 2.
DT   16-OCT-2019, entry version 91.
DE   RecName: Full=Putative mitochondrial ATP-dependent helicase irc3;
DE            EC=3.6.4.-;
GN   Name=irc3; ORFNames=SPBC11C11.11c, SPBC3B8.12;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales;
OC   Schizosaccharomycetaceae; Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M.,
RA   Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A.,
RA   Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G.,
RA   Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K.,
RA   James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J.,
RA   Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C.,
RA   Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E.,
RA   Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S.,
RA   Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K.,
RA   Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S.,
RA   Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B.,
RA   Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S.,
RA   Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D.,
RA   Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R.,
RA   Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B.,
RA   Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S.,
RA   Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M.,
RA   Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G.,
RA   Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J.,
RA   Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L.,
RA   Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J.,
RA   Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the helicase family. IRC3 subfamily.
CC       {ECO:0000305}.
DR   EMBL; CU329671; CAA20693.2; -; Genomic_DNA.
DR   RefSeq; XP_001713145.1; XM_001713093.1.
DR   BioGrid; 276171; 10.
DR   STRING; 4896.SPBC11C11.11c.1; -.
DR   REBASE; 190417; Bce021ORF874P.
DR   MaxQB; Q1MTR1; -.
DR   PaxDb; Q1MTR1; -.
DR   PRIDE; Q1MTR1; -.
DR   EnsemblFungi; SPBC11C11.11c.1; SPBC11C11.11c.1:pep; SPBC11C11.11c.
DR   EuPathDB; FungiDB:SPBC11C11.11c; -.
DR   PomBase; SPBC11C11.11c; irc3.
DR   HOGENOM; HOG000180925; -.
DR   InParanoid; Q1MTR1; -.
DR   OMA; RDYQEEC; -.
DR   PhylomeDB; Q1MTR1; -.
DR   PRO; PR:Q1MTR1; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005759; C:mitochondrial matrix; ISO:PomBase.
DR   GO; GO:0000346; C:transcription export complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; ISS:PomBase.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0032042; P:mitochondrial DNA metabolic process; ISO:PomBase.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Helicase; Hydrolase; Mitochondrion;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN         1    606       Putative mitochondrial ATP-dependent
FT                                helicase irc3.
FT                                /FTId=PRO_0000353817.
FT   DOMAIN       40    201       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      246    398       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND      53     60       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   MOTIF       148    151       DEAH box.
SQ   SEQUENCE   606 AA;  68943 MW;  97F729852B824547 CRC64;
     MLLNACCKKN LWPRNGSTIF RRFALKLRPY QEECLSACLN AFDEGKRRIA VSLATGSGKT
     ALFPHFIKYA PTLRPNSEQC LILVHRKELA LQALKHCRES LPNKSIEIDM GNQCASGLAD
     VTVASVFSLK NERLLKYNPL NFKLLIFDEV HHMASPSYLR ILEHFGAESE KSKVNVIGLT
     ATLFRADGKG LACGLDEIVY HRHFVDMIKD NWLVEPKVIN IKWSTDLVLA DSSSFLDQEK
     LKKEAQSEKA IFEIPRAWLE HASNRSSTLV FCINVEHSLK VCNAFRKLGI DARALFGETN
     DSERETLIQD FRKKKFPVLV NCMVLTEGTD IPNIDCLMIA RPTSSPNLLT QMIGRGLRLH
     EGKRDCLILD FCDSLRRVSL HVDPTLAGLS PDEVENFYNK SKNSLANPDY DPKIYGLQSV
     LWYSKLRKLI EMMDNIKNKD RSIFNLSTNA WVAVGMGRYV LSFLQKVLII DTNFEDGTHK
     ISEYTKEKLG TRVYNRKRIV SDRIPSLKFA IRAAETYISN LKTPRSLISR KAVWRMRPAS
     VRQINFLKKS NLKLDEKLLT AGVAADMITK VIYGGKGRQV RTDKLQSYLK HDANLKRITT
     LKELKG
//
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