ID   Q1QGZ4_NITHX            Unreviewed;       946 AA.
AC   Q1QGZ4;
DT   16-MAY-2006, integrated into UniProtKB/TrEMBL.
DT   16-MAY-2006, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   OrderedLocusNames=Nham_3783 {ECO:0000313|EMBL:ABE64503.1};
OS   Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Nitrobacter.
OX   NCBI_TaxID=323097 {ECO:0000313|EMBL:ABE64503.1, ECO:0000313|Proteomes:UP000001953};
RN   [1] {ECO:0000313|EMBL:ABE64503.1, ECO:0000313|Proteomes:UP000001953}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10229 / NCIMB 13809 / X14
RC   {ECO:0000313|Proteomes:UP000001953};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L.,
RA   O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T.,
RA   Gentry M.E., Bruce D., Richardson P.;
RT   "Complete sequence of chromosome of Nitrobacter hamburgensis X14.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; CP000319; ABE64503.1; -; Genomic_DNA.
DR   RefSeq; WP_011512135.1; NC_007964.1.
DR   AlphaFoldDB; Q1QGZ4; -.
DR   STRING; 323097.Nham_3783; -.
DR   KEGG; nha:Nham_3783; -.
DR   eggNOG; COG0323; Bacteria.
DR   eggNOG; COG4191; Bacteria.
DR   HOGENOM; CLU_012281_1_0_5; -.
DR   OrthoDB; 9816482at2; -.
DR   Proteomes; UP000001953; Chromosome.
DR   GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR   CDD; cd00075; HATPase; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 2.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   PANTHER; PTHR44936:SF9; SENSOR HISTIDINE KINASE GLNK; 1.
DR   PANTHER; PTHR44936; SENSOR PROTEIN CREC; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF13589; HATPase_c_3; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 2.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:ABE64503.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001953};
KW   Transferase {ECO:0000313|EMBL:ABE64503.1}.
FT   DOMAIN          713..937
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   946 AA;  105263 MW;  E099F94657DA773C CRC64;
     MMARPQSNFR GKQLDFEEFR DLTFIGMAGL TDYLMKPAAP PNPNGMVNYR LVADSLGLTY
     EPDWLDRLGH ELDNGYESIA SHDSPSKDHA EDEHWVYLNS GFERIASLLY EKYYVPPPIR
     DLSYEEFRDV FLFELAGMVQ DSIGEDGRSH DRQKPLSYDL RVTADFLNLP HEPDWLARVT
     SEFLERGFIA RSDDSSGSPR YALTRQGYEH TDHLSEKLSA GNGFLLLHGE GTLFFSVDAS
     HISRLGLELV AKQETAVAEL VKNGYDADAT QVDLIFNTAS APQTSLEIYD NGSGMNIEQL
     EAGFMRLSTP NKVEHSRSEL FARQKAGRKG IGRFAAQRLG RRLVLETTTH SARNGLRLDI
     DWDEFVANRN LSAVPSKITR IKKPFEHGTR LTILDLRDSW SDAQIERSHR HIAELIQPFP
     LAAATASGAD PGFKASFARE RSGDLEIVAD DWSAFFRHAL AEIEGFVDHA GNASWTLKST
     QFGIDSGPST IGPNKDTPAE PYPHLKNVRF KAYYYIDKET QRAFRSKVAD KLQSSGGIRL
     YRNGFRVLPY GERFDDWLKL NASNLLRKVL PPHSNRNFLG FVEISDVDGT NFEETSSREG
     LLENESFVEL KDFVSAVLKT AILPIAAARD RKLTTTDTRQ KQRSPKGQAE ELLGRLSALQ
     KNANGDPAYT LALAQVVDAI RSSVIEIGDT GQALLEELGM MRVLATLGLT IGEFTHEIRI
     TLESVKASAS LLAASVQTEA SQPKQADALL DKIADFEGYL TYFDATVRDN VSREVVALEI
     RDVVNSFVKV VSPKLNRKEL TLETAFQGVS LFTRPMHKSE WASILINLFT NSLKAIRRAG
     VNGRIQIECG RNEGNIFLDF MDNGDGIPAT DATRIFDAFF TTTWATGASA EDGTFEGMGM
     GLKIVKDIVE TARGQIALRP AAEGFSTCFR VSVPEASDEE IPDNAY
//