ID Q1QK67_NITHX Unreviewed; 376 AA.
AC Q1QK67;
DT 16-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Dolichyl-phosphate beta-D-mannosyltransferase {ECO:0000313|EMBL:ABE63380.1};
DE EC=2.4.1.83 {ECO:0000313|EMBL:ABE63380.1};
GN OrderedLocusNames=Nham_2598 {ECO:0000313|EMBL:ABE63380.1};
OS Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Nitrobacter.
OX NCBI_TaxID=323097 {ECO:0000313|EMBL:ABE63380.1, ECO:0000313|Proteomes:UP000001953};
RN [1] {ECO:0000313|EMBL:ABE63380.1, ECO:0000313|Proteomes:UP000001953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10229 / NCIMB 13809 / X14
RC {ECO:0000313|Proteomes:UP000001953};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L.,
RA O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T.,
RA Gentry M.E., Bruce D., Richardson P.;
RT "Complete sequence of chromosome of Nitrobacter hamburgensis X14.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006739}.
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DR EMBL; CP000319; ABE63380.1; -; Genomic_DNA.
DR RefSeq; WP_011511046.1; NC_007964.1.
DR AlphaFoldDB; Q1QK67; -.
DR STRING; 323097.Nham_2598; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR KEGG; nha:Nham_2598; -.
DR eggNOG; COG0463; Bacteria.
DR eggNOG; COG2246; Bacteria.
DR HOGENOM; CLU_039727_0_0_5; -.
DR OrthoDB; 9807795at2; -.
DR Proteomes; UP000001953; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004582; F:dolichyl-phosphate beta-D-mannosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd06442; DPM1_like; 1.
DR InterPro; IPR039528; DPM1-like.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR007267; GtrA_DPMS_TM.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43398:SF2; DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43398; DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR Pfam; PF04138; GtrA; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000313|EMBL:ABE63380.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001953};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABE63380.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 254..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..186
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
FT DOMAIN 257..373
FT /note="GtrA/DPMS transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04138"
SQ SEQUENCE 376 AA; 41151 MW; 5E95788E4F8F2CB6 CRC64;
MNEAIRPAPV DPSTGMPRQL SVVVPTFNER DNVVALYRKL SAALTGIAWE AIYVDDNSPD
GTFDVVRKLA AIDPRVRCIR RIGRRGLSGA CIEGILASSA PCTAVMDADL QHDETRLPKM
LALLESDAAD LVVGSRYIEG GSADSFDKQR AGFSMLATSV AKRLLHIEIA DPMSGFFMIR
RDRFEQLAPE LSIQGFKILL DVIATARGAL RVTEIPFTFG SRLHGESKLD SMVALDFLGL
VLAKLTRDAV SLRFLLFALV GSVGVVVHFA GLFVALDALR WPFPHSQAFG AVLAMTSNFL
LNNFLTYRDQ RLKGIGILRG LLVFYLVCSV GLLANVGVAF SVYNQEPIWW LAGAAGALMG
VVWNYAVSSL FVWRRR
//
