ID Q20805_CAEEL Unreviewed; 299 AA.
AC Q20805;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1996, sequence version 1.
DT 27-MAR-2024, entry version 148.
DE SubName: Full=Nematode cuticle collagen N-terminal domain-containing protein {ECO:0000313|EMBL:CAA98486.1};
GN Name=col-154 {ECO:0000313|EMBL:CAA98486.1,
GN ECO:0000313|WormBase:F55C10.2};
GN ORFNames=CELE_F55C10.2 {ECO:0000313|EMBL:CAA98486.1}, F55C10.2
GN {ECO:0000313|WormBase:F55C10.2};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAA98486.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAA98486.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAA98486.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBUNIT: Collagen polypeptide chains are complexed within the cuticle
CC by disulfide bonds and other types of covalent cross-links.
CC {ECO:0000256|ARBA:ARBA00011518}.
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DR EMBL; BX284605; CAA98486.1; -; Genomic_DNA.
DR PIR; T22705; T22705.
DR RefSeq; NP_505886.1; NM_073485.5.
DR AlphaFoldDB; Q20805; -.
DR SMR; Q20805; -.
DR DIP; DIP-27073N; -.
DR STRING; 6239.F55C10.2.1; -.
DR PaxDb; 6239-F55C10-2; -.
DR PeptideAtlas; Q20805; -.
DR EnsemblMetazoa; F55C10.2.1; F55C10.2.1; WBGene00000727.
DR GeneID; 186300; -.
DR KEGG; cel:CELE_F55C10.2; -.
DR UCSC; F55C10.2; c. elegans.
DR AGR; WB:WBGene00000727; -.
DR WormBase; F55C10.2; CE05952; WBGene00000727; col-154.
DR eggNOG; KOG3544; Eukaryota.
DR GeneTree; ENSGT00970000196049; -.
DR HOGENOM; CLU_001074_4_2_1; -.
DR InParanoid; Q20805; -.
DR OMA; HQITREM; -.
DR OrthoDB; 2883876at2759; -.
DR PhylomeDB; Q20805; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00000727; Expressed in larva and 3 other cell types or tissues.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042302; F:structural constituent of cuticle; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR InterPro; IPR002486; Col_cuticle_N.
DR InterPro; IPR008160; Collagen.
DR PANTHER; PTHR24637:SF302; COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR24637; COLLAGEN; 1.
DR Pfam; PF01484; Col_cuticle_N; 1.
DR Pfam; PF01391; Collagen; 2.
DR SMART; SM01088; Col_cuticle_N; 1.
PE 4: Predicted;
KW Collagen {ECO:0000313|EMBL:CAA98486.1};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..64
FT /note="Nematode cuticle collagen N-terminal"
FT /evidence="ECO:0000259|SMART:SM01088"
FT REGION 107..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..162
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..236
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 299 AA; 29280 MW; 59F864183BE937B2 CRC64;
MEFEQRIKAY RFVAYSAVAF SVVAVLSVCI TLPMVHNYVH HVKRTMNQEV QFCRGSAKDI
WTEVNELKSI QHANRTARQA GYDAGVNGGS ASAGGCDACC LPGAAGPAGT PGKPGRPGKP
GAPGLPGNPG RPPQQPCDPI TPPPCQPCPQ GPPGPPGPPG PSGDAGGNGN PGSPGQDGQP
GAPGNKGPSG PNGNPGAPGA PGQPGQDAPS EPITPGAPGP QGTPGPQGPP GQPGQPGHDG
QPGAPGPKGP NGNPGQPGAD GNPGAPGQSG TPGGVGEKGI CPKYCAIDGG VFFEDGTRR
//
