ID Q21L96_SACD2 Unreviewed; 490 AA.
AC Q21L96;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Mannitol dehydrogenase-like protein {ECO:0000313|EMBL:ABD80533.1};
GN OrderedLocusNames=Sde_1271 {ECO:0000313|EMBL:ABD80533.1};
OS Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC Cellvibrionaceae; Saccharophagus.
OX NCBI_TaxID=203122 {ECO:0000313|EMBL:ABD80533.1, ECO:0000313|Proteomes:UP000001947};
RN [1] {ECO:0000313|EMBL:ABD80533.1, ECO:0000313|Proteomes:UP000001947}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2-40 / ATCC 43961 / DSM 17024
RC {ECO:0000313|Proteomes:UP000001947};
RX PubMed=18516288; DOI=10.1371/journal.pgen.1000087;
RA Weiner R.M., Taylor L.E.II., Henrissat B., Hauser L., Land M.,
RA Coutinho P.M., Rancurel C., Saunders E.H., Longmire A.G., Zhang H.,
RA Bayer E.A., Gilbert H.J., Larimer F., Zhulin I.B., Ekborg N.A., Lamed R.,
RA Richardson P.M., Borovok I., Hutcheson S.;
RT "Complete genome sequence of the complex carbohydrate-degrading marine
RT bacterium, Saccharophagus degradans strain 2-40 T.";
RL PLoS Genet. 4:E1000087-E1000087(2008).
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DR EMBL; CP000282; ABD80533.1; -; Genomic_DNA.
DR RefSeq; WP_011467753.1; NC_007912.1.
DR AlphaFoldDB; Q21L96; -.
DR STRING; 203122.Sde_1271; -.
DR KEGG; sde:Sde_1271; -.
DR eggNOG; COG0246; Bacteria.
DR HOGENOM; CLU_027324_0_1_6; -.
DR OrthoDB; 271711at2; -.
DR Proteomes; UP000001947; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0019594; P:mannitol metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR000669; Mannitol_DH.
DR InterPro; IPR013118; Mannitol_DH_C.
DR InterPro; IPR023027; Mannitol_DH_CS.
DR InterPro; IPR013131; Mannitol_DH_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43362:SF1; MANNITOL DEHYDROGENASE 2-RELATED; 1.
DR PANTHER; PTHR43362; MANNITOL DEHYDROGENASE DSF1-RELATED; 1.
DR Pfam; PF01232; Mannitol_dh; 1.
DR Pfam; PF08125; Mannitol_dh_C; 1.
DR PRINTS; PR00084; MTLDHDRGNASE.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00974; MANNITOL_DHGENASE; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001947}.
FT DOMAIN 31..189
FT /note="Mannitol dehydrogenase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01232"
FT DOMAIN 218..466
FT /note="Mannitol dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08125"
SQ SEQUENCE 490 AA; 53632 MW; 3B16DC5A1CB3AC02 CRC64;
MSNLHLNYES LSNVLDPVKK PQYTPSEHRS GIVHIGIGAF HKAHQAVFTD DVLNMHGGDW
RITAVSLRRP DARDQLEKQN SLYTVVEKSD GEISPRIIGA VEKVLVCPED PQQVINTIAS
TDIKIVSLTI TEKGYCQKNG TLDTSNVDIA HDLNNLSAPK SMPGLIVAAC AARKQNNANG
FTVLSCDNLP HNGKITQNVV MRFAEKVDAE LASWIATHIS FCSTMVDRIV PATTSADLDE
VKNLIGLADD AAVICEPFRQ WVIEDNFVAG RPQWEDAGAL LVADVTPYED MKLRLLNGSH
SALAYLGFLS GFDFIHQAIA NPRLLALTKK LMDEDVTPTL NVPSGFDLDA YKAIIRTRFA
NSRVPYKTTQ VANDGSQKLP QRILAVADHL ISGGKQPAVI PAIIAAWFQF LEGQDTHGEQ
HTVNDPLANT LCPLALKHKA NDTKQVQELV AASQIFPEGL IANTEFINSI EHYLAKFHAK
GVLTTLAELN
//
