ID Q22468_CAEEL Unreviewed; 626 AA.
AC Q22468;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2004, sequence version 2.
DT 27-MAR-2024, entry version 165.
DE SubName: Full=GH18 domain-containing protein {ECO:0000313|EMBL:CAA91419.2};
GN Name=cht-2 {ECO:0000313|EMBL:CAA91419.2,
GN ECO:0000313|WormBase:T13H5.3};
GN ORFNames=CELE_T13H5.3 {ECO:0000313|EMBL:CAA91419.2}, T13H5.3
GN {ECO:0000313|WormBase:T13H5.3};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAA91419.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAA91419.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAA91419.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284602; CAA91419.2; -; Genomic_DNA.
DR PIR; T24898; T24898.
DR RefSeq; NP_495798.2; NM_063397.3.
DR AlphaFoldDB; Q22468; -.
DR SMR; Q22468; -.
DR STRING; 6239.T13H5.3.1; -.
DR CAZy; CBM18; Carbohydrate-Binding Module Family 18.
DR CAZy; GH18; Glycoside Hydrolase Family 18.
DR EPD; Q22468; -.
DR PaxDb; 6239-T13H5-3; -.
DR PeptideAtlas; Q22468; -.
DR EnsemblMetazoa; T13H5.3.1; T13H5.3.1; WBGene00011757.
DR GeneID; 174363; -.
DR KEGG; cel:CELE_T13H5.3; -.
DR UCSC; T13H5.3; c. elegans.
DR AGR; WB:WBGene00011757; -.
DR WormBase; T13H5.3; CE36953; WBGene00011757; cht-2.
DR eggNOG; KOG2806; Eukaryota.
DR HOGENOM; CLU_450037_0_0_1; -.
DR InParanoid; Q22468; -.
DR OMA; CCGKYGY; -.
DR OrthoDB; 3128703at2759; -.
DR PhylomeDB; Q22468; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00011757; Expressed in pharyngeal muscle cell (C elegans) and 3 other cell types or tissues.
DR GO; GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd10909; ChtBD1_GH18_2; 3.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.30.60.10; Endochitinase-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR001002; Chitin-bd_1.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR036861; Endochitinase-like_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR46073; CHITINASE; 1.
DR PANTHER; PTHR46073:SF4; CHITINASE; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00270; ChtBD1; 3.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 1: Evidence at protein level;
KW Chitin-binding {ECO:0000256|ARBA:ARBA00022669};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q22468};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..626
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004201122"
FT DOMAIN 32..393
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
SQ SEQUENCE 626 AA; 70107 MW; 4B4BBDA79F86D984 CRC64;
MRFVMWMWLF VVWITVLFGV SNGGILDRSC GRRRVGYITS WGKHPFRDDQ AEKLTHLVFA
FFVVDSDGSV KLEGDAAKAR LEHVKEVASR HPDLKLLYAV GGWENSQYFS VLTADHSRRS
ILISNFVKVI KEYGFDGVDI DWEYPVTGGA VEGTPADRRN YVNLMRELRN ELRDLESETG
KSYLISFAGA AGHWVLKPGY DLQQLMKYCD FVNVMSYDYF GAWASKWGAY TGPPAPLQFA
MPKKFSGRMN VHATMKDYSC QIKATDKINM GVPFYGRFWK NVGDAVDSTD DMWRTATATN
SEGTKFEGGD VQWRDLHEKF DTTKTKFHSG SKTPFIWLSE QKTFVGYENA ESLKHKVDYI
VENNIGGVMI WAIDFDDDQG TLLNSAAAES ICTTSTKSFN YKCSPVDDKR WWTYDDNEEL
AGMCGKSSPL IDGYYPVCDP DDPGHACCGK YGYCGSGAEF CSCPECIDYG ADPNLILKEP
VKPSQKITWY TSDAGEGKRG RCGRDVPPLE GEAPTCNPDD ANAHCCSNGG YCGNSKEHCE
CNGCIDFAKQ RDFKYKPLEW WTFSENPANV GRCGYNAPRL STGKIPKCDP DSESYCCSNS
GYCGKGEQYC SCLGCADFKA NPAFEY
//
